Sharma RK (1995) Signal transduction: regulation of cAMP concentration in cardiac muscle by calmodulin-dependent cyclic nucleotide phosphodiesterase. Mol Cell Biochem 149–150:241–247Sharma R. K. (1995) Signal transduction: regulation of cAMP concen- tration in cardiac muscle by calmodulin-dependent ...
consistent with i) the time lag (12 h) observed between the start of IL-1β-treatment and the development of a cAMP-dependent stellate cell morphology; and ii) our previous results showing that PGE2 acts in synergy with IL-1β to enhance the phenotypic transition in smooth muscle cells [...
39, 43, 44 In vivo studies reveal that knockout of the EPAC1 gene can attenuate neointima formation by inhibition of smooth muscle cells migration, in the meantime, Ca2+ concentration and cofilin-mediated lamellipodia formation are decreased.45 Most recently, Cheng and co-workers found that EPAC...
Genetic manipulation and functional analysis of cAMP signalling in cardiac muscle: implications for a new target of pharmacotherapy: Figure 1 Ishikawa,Y.,Iwatsubo,... - 《Biochm.soc.trans》 被引量: 0发表: 2005年 Variation in Lignin Content and Composition (Mechanisms of Control and Implications...
“I think the age-old battle between coaches and personnel people, as far as rookies vs. veterans, gets enhanced this year,” Mayock said. “Coaches traditionally trust veterans that they’ve seen do it in the past. The way a rookie earns that trust is throughout the offseason program, ...
Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study Article Open access 14 December 2014 Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker ...
cardiac muscle (Mr = 56,000) and rabbit skeletal muscle (Mr = 48,000) displayed completely different patterns as expected for the cAMP-binding components of types II and I protein kinases. Both phospho- and dephospho-cAMP-binding components from the purified bovine cardiac muscle protein kinase...
Fib( myofib transformation was assessed by a-smooth muscle actin (α-SMA) expression. Results: Epacl protein was highly expressed in CF. Treatment with transforming growth factor β(TGFβ) decreased but with AM increased adenylyl cyclase 6 (AC6) mRNA and Epacl protein expression. AM, ...
ScienceDirect® is a registered trademark of Elsevier B.V. Cookies are used by this site. To decline or learn more, visit our Cookies page Switch to Mobile Site Recommended articles No articles found. Citing articles (0) This article has not been cited. Related book content No ...
In the myocardium of many patients with symptoms of heart failure there is a decrease in beta-adrenoceptor number, accompanied by a reduction in responsiveness to beta-agonists [3,5,8,10,16]. The hypothesis that this results simply from exposure to high