ligands capable of binding a calcium dependent binding protein, that comprise an amino acid sequence corresponding to that of a wild type ligand for the calcium dependent binding protein, with a modification which results in enhanced affinity of the ligand for the calcium dependent binding protein.NE...
Calcium-binding protein 1CalmodulinPresynapticCalcium channelGlutamate receptorPresynaptic group III metabotropic glutamate receptors (mGluRs) and Ca2+ channels are the main neuronal activity-dependent regulators of synaptic vesicle release, and they use common molecules in their signaling cascades. Among ...
The cytoplasmic amino terminus of HCN1, the primary full-length HCN isoform expressed in trout saccular hair cells, was found by yeast two-hybrid protocols to bind the cytoplasmic carboxyl-terminal domain of a protocadherin 15a-like protein. HCN1 was immunolocalized to discrete sites on saccular...
Annexin A4 (Anx4) is a cytosolic calcium-binding protein with four repeat domains, each containing one calcium-binding site (CBS). The protein interacts with the phospholipid membrane through the CBS-coordinated calcium ion, although the role of each CBS in the calcium-dependent association is ...
Complex, multiprotein forms of bovine (calf thymus), hamster (Chinese hamster ovary cell), and human (HeLa) cell DNA polymerase α (Polα) were analyzed for their content of calmodulin-binding proteins. The approach used an established autoradiographic technique employing 125I-labeled calmodulin to...
Rapid metabolic reprogramming mediated by the AMP-activated protein kinase during the lytic cycle of Toxoplasma gondii Yaqiong Li Zhipeng Niu Bang Shen Nature Communications (2023) Effect of deleting four Toxoplasma gondii calcium-binding EGF domain-containing proteins on parasite replication and virulen...
This protein kinase requires an endogenous cytosolic, heat-stable protein for activity. This protein is shown to be identical to calmodulin, a ubiquitous calcium-binding protein, known to be involved in regulation of a variety of calcium-dependent processes. Authentic calmodulin and the endogenous ...
Here we show that one of the released proteins is calpactin I, a calcium-dependent phospholipid-binding protein known to promote in vitro aggregation of ... T Sarafian - 《Journal of Cell Biology》 被引量: 318发表: 1991年 Two related but distinct forms of the Mr 36,000 tyrosine kinase ...
Further, unphosphorylated pre-IL-1α showed no calcium-dependent binding to acidic phospholipids at concentrations below 5 × 10 6 M. These results ... N Watanabe,Y Kobayashi - 《Febs Letters》 被引量: 3发表: 1995年 Phosphorylation sites of protein kinase C δ in H2O2-treated cells and it...
The discovery of the calcium-binding protein calmodulin in plants (Anderson and Cormier, 1978; Anderson et al., 1980) provided the basis for suggesting that Ca 2+ serves a second messenger role in plants, and that Ca 2+ -dependent metabolic regulation in plant cells may be mediated by such...