1、第22章 钙通道阻滞药 Calcium Channel Blockers,钙通道阻滞药(calcium channel blockers) 是一类阻滞Ca2+从细胞外液经电压依赖性钙通道流入细胞内的药物, 又称钙拮抗药(Calcium antagonists)。 【钙通道的生理意义及分类】 1. Ca2+的生理意义 : 参与多种生理生化反应,在生物信息传递和内环境稳定中,起极为...
1、细胞外侧细胞外侧细胞内侧细胞内侧IIIIIIIV6DHPPAA(DHP)苯烷胺类药物结合位点苯烷胺类药物结合位点二氢吡啶类药物结合位点二氢吡啶类药物结合位点钙通道钙通道亚单位的分子结构亚单位的分子结构世界卫生组织世界卫生组织(WHO)的分类的分类一、选择性一、选择性Ca2+拮抗药拮抗药 作用于作用于L-型型Ca2+通道通道 1...
钙通道阻滞剂(Calciumchannelblockers)Ca2+isthekeycomponentofthecontractioncouplingbetweenthemyocardiumandthevascularsmoothmuscle.Theincreaseofintrac..
In 1883, Ringer showed that to get isolated hearts to contract, it was necessary to have Ca2+ ions in the perfusion medium [421]. This was the first demonstration of the critical role of calcium in cellular activity. Remarkably, a hundred years passed be
Since its discovery more than 40 years ago, calcium channel blockers have been widely studied and used in cardiovascular medicine. Apart from their ability to reduce blood pressure they have been implemented in the treatment of various forms of angina pectoris (e.g. in patients with stable coron...
Thus, it appears that the prophylactic effects of calcium-channel blockers such as nimodipine and flunarizine are comparable to, if not better than, those achieved with some of the more frequently prescribed migraine preventives. 展开 关键词:...
Calcium channel blocker 来自 Google Patents 喜欢 0 阅读量: 27 公开/公告号: US5435998 A 公开/公告日期: Jul 25, 1995 发明人: MB Abelson 关键词: intestinal angina mesenteric angiography 被引量: 49 摘要: Low-tension glaucoma is treated by topical administration to the eye of an ...
网络钙通道阻滞剂;钙通道阻滞药;钙通道拮抗剂 网络释义
Pre-treatment of root cells with the Ca2+ chelator/channel blockers/antagonist not only alleviated Al3+-induced DNA damage and cell death induced but also blocked the Al3+-mediated adaptive response to genotoxic stress induced by MMCl and EMS. For the first time, the results of the present ...
calciumchannelblocker激活态选择性通道 钙通道阻滞药 (calciumchannelblockers) 目的要求: 1.掌握钙通道阻滞药的概念、基本作用、用 途及主要不良反应; 2.熟悉硝苯地平、地尔硫卓、维拉帕米的特 点; 3.了解Ca2+的生理意义及钙拮抗剂的分类,钙通道阻滞药作用机制及特点。 calciumchannelblockers,alsonamed calciuman...