钙泵的本质是一种调节钙在生物膜间转移的结构或机制,主要由Ca2+-三磷酸腺苷酶(Ca2+-ATPase)在细胞膜上组装而成。例如,在红细胞中,质膜上的钙泵负责将胞质中的游离钙离子排出体外;而在肌红细胞中,肌质网上的钙泵则负责将钙离子从肌浆运输到肌质网内部,以维持特定的生理功能。
性质:调节钙在生物膜中的激活转移的结构或机制。它是由Ca2+-三磷酸腺苷酶(Ca2+-ATPase)在膜上组装而成。在红细胞质膜上的钙泵把胞质游离Ca2+输送到胞外;在肌红细胞,肌质网上的钙泵把Ca2+从肌浆运输到肌质网内。 2结构与功能 Ca2+泵分布在动,植物细胞质膜,线粒体内膜,内质网样囊膜(SER-like organelle)...
钙泵(calcium pump,Ca²+-ATPase) 9600:15 负染色(negative staining) 5000:14 封闭连接(occluding junction) 9800:15 分子开关(molecular switch) 15300:14 分子伴侣(chaperone,molecular chaperon) 19600:16 分泌途径(secretory pathway) 5200:21 多线染色体(polytene chromosome) 5400:11 多聚核糖体(polyribosome...
Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis . Mol Cancer Ther 9 , 718–730 (2010).Law BY, Wang M, Ma DL, Al-Mousa F, Michelangeli F, Cheng SH...
XENON REDUCES Ca++ -ATPase PUMP ACTIVITY IN SYNAPTIC PLASMA MEMBRANES FROM THE RAT BRAIN.Critically reflective research approachFood systemsPedagogySocial constructivismStudent inquiryTransformative learningAn abstract is unavailable. This article is available as a PDF only.doi:10.1097/00000542-199209001-...
The plasma membrane Ca2+-ATPase pump (PMCA) is an integral component of the Ca2+ signaling system which participates in signal transduction during agonist stimulated cell activation. To better understand the physiological function of the pump, isoform 1a (PMCA1a) was over-expressed in rat aortic ...
D. 在平滑肌细胞内,L精氨酸在NO合酶催化作用下生成NO 答案:D 解析:血管内皮细胞和神经细胞是NO的生成细胞,NO再经扩散进入平滑肌细胞发挥作用。 解析:空 5、论述题(20分,每题5分) 1. Ca2+泵(Ca2+pump,Ca2+ATPase)的结构和作用原理如何?反馈 收藏 ...
A plasma membrane Ca(2+)-pump ATPase preparation purified from porcine aorta was incubated with cGMP-dependent protein kinase (G-kinase) under the conditions under which dose-dependent stimulation of the enzyme by G-kinase was observed. Several proteins were phosphorylated, but two isoforms of plas...
Under certain conditions, this rate of ATP loss can be taken as a measure of the Ca pump ATPase activity of intact RBCs. From RBC fractionation studies it appeared that the defective Ca pump ATPase was acquired during the relatively short life-span of the hemolytic RBC. Significant loss of ...