Objectives: Regarding the relationship between type 2 diabetes and hereditary chromatists, we conducted a genetic analysis on two previously reported mutations C282Y and H63D related to the HFE gene in our population. Patients and Methods: Altogether, 145 patients with type 2 diabetes and 145 ...
Hemochromatosis mutations C282Y and H63D in `cis' phase. Clin Genet 2001;60:68-72.Best, L. G., Harris, P. E., and Spriggs, E. L. (2001) Hemochro- matosis mutations C282Y and H63D in `cis' phase. Clin. Genet. 60, 68 -72...
Distribu- tion of the C282Y and H63D polymorphisms in hereditary hemochro- matosis patients from the French Basque Country. Ann Hema- tol. 2005;84(2):99-102. doi: 10.1007/s00277-004-0957-5. [PubMed: 15503019].Bauder F, Scribans C, Degioanni A, Renoux M, Dutour O (2005) ...
The aim of this study was to determine the association between HFE gene C282Y and H63D mutations and liver cirrhosis in the Lithuanian population. This was the first study assessing the prevalence of HFE gene mutations in Lithuanian cirrhotic patients and adds additional insights on the impact of...
We sought to compare frequencies of HFE C282Y and H63D alleles and associated odds ratios (OR) in 100 consecutive unrelated white adults with malignancy to those in 318 controls. Data from patients with more than one malignancy were analyzed according to
We used a prospective population-based cohort study to estimate the prevalence of elevated iron indices and hemochromatosis-related morbidity for compound heterozygotes. In all, 31,192 subjects of northern European descent were genotyped for HFE C282Y and H63D. An HFE -genotype stratified random ...
The gene responsible for hereditary hemochromatosis close to the human leukocyte antigen A locus was previously identified and designated as HFE. This study was performed to evaluate the clinical significance of two mutations, C282Y and H63D of HFE, in Japanese patients with hepatic iron overload....
Objective:The gene responsible for hereditary hemochromatosis close to the human leukocyte antigen A locus was previously identified and designated as HFE. This study was performed to evaluate the clinical significance of two mutations, C282Y and H63D of HFE, in Japanese patients with hepatic iron ...
Taylor And FrancisScandinavian Journal of RheumatologyCarroll G, Sharma G, Upadhyay A, Jazayeri J. Ferritin concen- trations in synovial fluid are higher in osteoarthritis patients with HFE gene mutations (C282Y or H63D). Scand J Rheuma- tol 2010;39:413-20....
NAFLD patients with C282Y, but not H63D mutations, had lower median serum hepcidin levels (57 versus 65 ng/mL; P = 0.01) and higher mean hepatocellular (HC) iron grades (0.59 versus 0.28; P 1.0, ≤2.5; P ≤ 0.041), compared to WT, but not with either HC or RES iron. NAFLD ...