This protocol providesa rapid and enantioselective pathway to access a novel class of structurallyimportant C2-quaternary indolin-3-ones that might be useful for drugdiscovery.doi:10.1021/acs.orglett.9b01823Shuaishuai FangShiyi JinRui MaTao Lu...
Enantioselective Nucleophilic Aromatic Substitution Reaction of Azlactones to Synthesize Quaternary α-Amino Acid Derivatives Li, Yi,Pan, Hao,Li, Wang-Yuren,... - 《Synlett》 - 被引量: 0 收藏相关文章 Chiral N,N′-Dioxide/Mg(OTf)2 Complex-Catalyzed Asymmetric [2,3]-Rearrangement of in situ Ge...
Palladium‐Catalyzed One‐Pot Synthesis of C2‐Quaternary Indolin‐3‐ones via 1H‐indole‐3‐sulfonates Generated in Situ from 2‐Alkynyl Arylazides and Sulfonic Acidspalladium-catalyzedindole derivatives2-alkynyl arylazidesN-containing heterocycles...
22 Abstract: A novel method for the synthesis of C2- 23 quaternary indole-3-ones via palladium-catalyzed 24 one-pot transformation of 2-alkynyl arylazides is 25 described. The reaction produced in moderate to 26 excellent yields under mild conditions. This novel 27 rearrangement of 1-H-indole...
Gold/Copper-Co-catalyzed Tandem Reactions of 2-Alkynylanilines: ASynthetic Strategy for the C2-Quaternary Indolin-3-onesA new strategy for direct and highly efficient synthesis of 2,3'-bisindolin-3-ones has been developed via a gold/copper-co-catalyzed tandem reactions of 2-alkynylanilines ...
An Integrative Approach to Study the Inhibition of Providencia vermicola FabD Using C2-Quaternary IndolinonesAnkita KhataniarAbhichandan DasManash J BaruahKusum K BaniaSanchaita RajkhowaSami A Al-HussainMagdi EA Zaki
palladium-catalyzedindole derivatives2-alkynyl arylazidesN-containing heterocyclesA novel method for the synthesis of C2-quaternary indole-3-ones via palladium-catalyzed one-pot transformation of 2-alkynyl arylazides is described. The reaction produced in moderate to excellent yields under mild conditions...
A direct strategy for intramolecular transfer oxygenation of alkynes and cycloisomerization of 2‐nitroalkynes to synthesize a wide range of C2‐quaternary indolin‐3‐ones was developed by a copper/diboron system. The desired allylation, benzylation and propargylation products were obtained in moderate...
An oxidative dearomatization chemistry of 2-arylindole via a unique pathway involving Pd-catalyzed C–H peroxygenation is documented. Coupled with cascade transformation, it provides a new route to access indolin-3-ones bearing a C2-quaternary functionality, including a chiral center (indoxyls), a...
Free (NH)﹊ndoles gave C2﹒uaternary indolinone derivatives whilst (NR)﹊ndoles yielded C3﹒uaternary indolinones as the major product. Moreover, the addition of excess amount of TBHP also facilitated the one﹑ot transformation of (NR)﹊ndoles to the corresponding isatin derivatives.doi:10.1002...