Results C1q+ TAMs highly expressed multiple inhibitory molecules and their high infiltration was significantly correlated with poor prognosis. C1q+ TAMs promote MPE immunosuppression through impairing the antitumor effects of CD8+ T cells. Mechanistically, C1q+ TAMs enhance fatty acid binding protein 5 (...
In addition, TAMs can recruit mast cells (MC), whose role is likely context-specific in BC and other solid tumors. MCs have been associated with both protumor and antitumor effects [8]. The C1q-Tumor Necrosis Factor Related protein (CTRP) family consist of adiponectin and fifteen (CTRP1-...
P-413 Inflammatory markers characterize neutrophils and C1q+ TAMs in the day 100 bone marrow aspirate post ASCT of patients with early progressiondoi:10.1016/S2152-2650(23)02030-XCaleb SteinTaxiarchis KourelisCharalampos CharalampousYuan Xiao Zhu...
The surface expression of biomarkers CD68 and CD206 on TAMs in samples obtained at diagnosis was compared with that in specimens obtained at first relapse. Based on the change in expression levels of CD68 and CD206 from diagnosis to relapse, patients were categorized into three groups:''...