学位论文作者:**日期:加D年妇名日 中文摘要急性髓系白血病患者NPMl、FLT3和C.KIT基因突变的检测及预后分析中文摘要背景与目的NPMl突变和FLT3.ITD突变都是成人急性髓系白血病(AML)患者最常见的基因突变,均倾向于发生在正常核型AML(NK.AML)患者。正常核型伴单独NPM突变的AML预后较好,但当合并FLT3一ITD突变时预后较差...
A mismatch amplification real-time PCR assay was developed and validated to test for the Asp816Val mutation. Subjects were recruited to four subject groups: normal non-atopics, atopics without anaphylaxis, food-induced anaphylactics and non-food anaphylactics. Blood samples collected from forty ...
The table includes the 50 patients on whom mutation screening was carried out. ND indicates not done (that is, blood sample was not available); NA, skin involvement unknown because the case report form was not available. 1 The presence of mutations was assessed by reverse transcription–PCR us...
STI571治疗CML的经验中在许多病例中是由于耐 factorleukemias:alIlItalina retrospectivestudy.BLOOD.2006:1o7: 3463～3468 药,显示缓解可能是部分和短暂的持续。仅应用小分 17N Boissele.Incidencenadprognosticimpactofc一 t.FLT3.nadRas 子药物抑制酪蛋 白激酶活性的转化来治愈疾病似乎 geneinu~tions incore...
& Urban, C. ( 2008 ) Successful treatment of progressive cutaneous mastocytosis with imatinib in a 2-year-old boy carrying a somatic KIT mutation . ... K.,M.,Hoffmann,... - 《Blood》 被引量: 65发表: 2008年 [Application of denaturing high performance liquid chromatography to mutation det...
Applications Tested: This 104D2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample ...
When interested in staining HSCs from peripheral blood, we recommend the use of clone 104D2. Please refer toProduct # 17-1178.^M ^M Applications Reported: YB5.B8 has been reported for use in flow cytometric analysis.^M ^M Applications Tested: The YB5.B8 antibody has been ...
STI571 appeared to be specific for GIST with KIT mutation, as in the EORTC trial,19 it was not effective to all non-GIST soft-tissue tumors that did not express c-kit. Furthermore, a recent study demonstrated that in late-stage metastatic GIST, different mutations within the KIT gene ...
Blood from healthy controls was obtained from the Hannover Medical School blood donation service. Human biopsies were obtained from patients with HOCM who have undergone myocardial surgery at the Hannover Medical School or from non-transplanted donor hearts (accident victims; Sydney Heart Bank, ...
Applications Tested: This 104D2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a fin...