C002 C-type lectin-like molecule-1 (CLL-1) and lineage infidelity marker expression as assessed by flow cytometry distinguishes normal and aberrant stem cells in myelodysplastic syndromes - ResearchGatedoi:10.1016/S0145-2126(09)70040-2T. Westers...
C-type lectin domain family 12 member A (CLEC12A), also known as C-type lectin-like molecule 1 (CLL1), dendritic cell-associated lectin 2 (DCAL-2), myeloid inhibitory C-type lectin-like receptor (MICL), killer cell lectin like receptor-1 (KLRL1) and CD371, is a member of the C-...
CLEC-1 is a C-type lectin-like molecule. Based on its protein sequence, it is predicted to be a type 2 transmembrane protein with an N-terminal cytoplasmic tail, a single transmembrane domain, and a C-terminal extracellular C-type lectin-like domain, that is separated from the transmembrane...
C-type lectin-like CD161, a class II transmembrane protein, is a surface receptor expressed by NK cells and T cells. In coeliac disease, CD161 was expressed more frequently on gluten-reactive CD4+T cells compared to other memory CD4+T cells isolated from the same tissue compartment. CD161...
Human and mouse DCAL-2 have been previously described as myeloid inhibitory C-type lectin (MICL)44 and C-type lectinlike molecule-1 (CLL-1),45 respectively. Compared with the primary CRD protein sequence of other C-type lectins, hDCAL-2 has the greatest identity to Dectin-1 (31%), C...
C-type-lectin-like domain CTLDcp: CTLD-containing protein DAS: distributed annotation system EMBP: eosinophil major basic protein EST: expressed sequence tag HMM: hidden Markov model MBP: mannose-binding protein Myr: million years NLSLH:
Brown, G. D. & Gordon, S. Immune recognition. A new receptor for β-glucans.Nature413, 36–37 (2001).This paper shows that β-glucan is a ligand of the DC-associated C-type lectin-like receptor dectin-1. ArticleCASPubMedGoogle Scholar ...
C-type lectins expressed on myeloid cells comprise a family of proteins that share a common structural motif, and some act as receptors in pathogen recognition. But just as the presence of leucine-rich repeats alone is not sufficient to define a Toll-like receptor, the characterization of C-ty...
C-type lectin like receptors, such as dectin-1, dectin-2, DC-specific intercellular adhesion molecule 3-grabbing nonintegrin, and mannose receptor, recognize many fungal-derived allergens and other structurally similar allergens derived from house dust mites (HDM). In some cases, the fungal ...
Fig. 1. Structure of DC-SIGN and L-SIGN proteins. The C-type lectins DC-SIGN and L-SIGN are type II transmembrane proteins. Their cytoplasmic tails contain internalization signals (di-leucine, tyrosine, and tri-acidic) which are involved in internalization of the lectin. The extracellular doma...