c-MYC peptide fragments detected by LC-MS/MS. 23 specific peptides corresponding to 51% of the c-MYC sequence were detected in the control sample. Ten specific peptides corresponding to 23% of the sequence were
C-Myc过表达在MM的发生和发展中起着关键的作用,目前认为MM中C-Myc过表达的机制有以5种:(1)染色体易位。涉及C-Myc异常表达的染色体易位情况在新诊断的MM患者中占20%～50%,这些易位涉及免疫球蛋白(immunoglobulin,Ig)基因位点和一些非Ig融合伴侣基因,如46序...
Gopal等[11]研究进一步表明,急性淋巴细胞白血病和急性非淋巴细胞白血病C-myc表达最强,慢粒(CML)、骨髓增殖异常综合症(MDS)和多发性骨髓瘤(MM)C-myc蛋白表达远低于急性白血病,但明显高于正常对照,淋巴瘤的C-myc表达最低,可能是由于瘤细胞很少累及骨髓所致。C-myc的异常表达与急性白血病的FAB分型无相关性,但c-myc m...
pCMV-C-Myc Cat. No.:D2672-1μgPack size: 100μg 1μg Price: 888.00RMB •Purpose Express target protein with C-terminal Myc tag in mammalian cell •Depositor Beyotime •Publication Song et al. ONCOTARGET. 2017Feb 7;8(6):9108-9122. •Sequence Information D2672 pCMV-C-Myc-seq....
c-myc, cmyc, c myc, transam, elisa, transcription factor, dna binding, non radioactive, activation, activated, consensus binding site, regulation, MAPKNameFormatCat No.Price Overview TransAM c-Myc Kits provide everything needed to study activated c-Myc, including a positive control extract. ...
Chou,R.H., Churchill,J.R., Mapstone,D.E. and Flubacher,M.M. (1991) Sequence-speci(R)c binding of a c-myc nuclear-matrix-associated region shows increased nuclear matrix retention after leukemic cell (HL-60) differentiation. Am. J. Anat., 191, 312±320....
RNA sequencing (RNA-seq) analysis of MKC8866-treated orXBP1knockdown PCa cells revealed that IRE1α-XBP1s is essential for c-MYC signaling, a central oncogenic regulatory pathway in PCa12,13. These results establish IRE1α-XBP1s signaling as a potential target for alternative treatment strategies...
c-Myc Tag多肽是c-Myc融合蛋白的替代品,在免疫分析实验中用于竞争性结合anti-c-Myc抗体,c-Myc Tag多肽与抗体的结合是特异性的,因此,c-Myc Tag多肽是一种温和的、理想试剂可用于洗脱与anti-Myc单抗结合的Myc-tag融合蛋白。 产品性质 多肽序列(Amino acid sequence)...
BMAL1 and MYC–MAXheterodimersreveal a basic helix–loop–helix (bHLH) domain[48,49]that is required to recognize E-box sequences[50,51]. This common E-box sequence could suggest that a rewiring may take place during tumorigenesis, whereby the balance of clock-controlled transcription can be...
C-MYC/MYC抗体 英文名称: Anti-C-MYC/MYC Antibody (Clone#OTI1A6) 产品规格: 50μl|100μl|150μl 发货周期: 1～3天 产品价格: 询价 本产品仅可用于科研实验,严禁用于其他非科研用途! 抗体名称Anti-C-MYC/MYC Antibody (Clone#OTI1A6) 指标别名bHLHe39;c Myc;c-Myc;MRTL;MYC;Myc proto oncogene ...