Gopal等[11]研究进一步表明,急性淋巴细胞白血病和急性非淋巴细胞白血病C-myc表达最强,慢粒(CML)、骨髓增殖异常综合症(MDS)和多发性骨髓瘤(MM)C-myc蛋白表达远低于急性白血病,但明显高于正常对照,淋巴瘤的C-myc表达最低,可能是由于瘤细胞很少累及骨髓所致。C-myc的异常表达与急性白血病的FAB分型无相关性,但c-myc m...
Homo sapiens MYC proto-oncogene, bHLH transcription factor (MYC), transcript variant 2, mRNA. 检索号 NM_001354870 注册号 NM_001354870.1 This sequence information is just for reference only. c-Myc/MYC 家族和工具试剂信息 基因家族 Basic helix-loop-helix proteins c-Myc/MYC 基因家族相关试剂...
KONG XiangHui,WANG XuZhen,GAN XiaoNi & HE ShunPing Institute of Hydrobiology,Chinese Academy of Sciences,Wuhan 430072,China; College of Life Science,Henan Normal University,Xinxiang 453007,China.The c-myc coding DNA sequences of cyprinids (Teleostei:Cypriniformes):Implications for phylogeny[J]. ...
C-Myc过表达在MM的发生和发展中起着关键的作用,目前认为MM中C-Myc过表达的机制有以5种:(1)染色体易位。涉及C-Myc异常表达的染色体易位情况在新诊断的MM患者中占20%～50%,这些易位涉及免疫球蛋白(immunoglobulin,Ig)基因位点和一些非Ig融合伴侣基因,如46序...
c-Myc Tag多肽是c-Myc融合蛋白的替代品,在免疫分析实验中用于竞争性结合anti-c-Myc抗体,c-Myc Tag多肽与抗体的结合是特异性的,因此,c-Myc Tag多肽是一种温和的、理想试剂可用于洗脱与anti-Myc单抗结合的Myc-tag融合蛋白。 产品性质 多肽序列(Amino acid sequence)...
Highly expressed Myc target genes also tended to be associated with the Myc cognate sequence CACGTG, the E-box, although this association was so loose as to preclude a rigid E-box requirement (Figure S4C). Indeed, canonical E-boxes themselves were relatively more restricted to the vicinity of...
c-myc, cmyc, c myc, transam, elisa, transcription factor, dna binding, non radioactive, activation, activated, consensus binding site, regulation, MAPKNameFormatCat No.Price Overview TransAM c-Myc Kits provide everything needed to study activated c-Myc, including a positive control extract. ...
The c-MYC oncogene is activated in over 70% of all human cancers. The intrinsic disorder of the c-MYC transcription factor facilitates molecular interactions that regulate numerous biological pathways, but severely limits efforts to target its function f
myc靶点下游cropped转录dmyc 图1c-Myc结构[2]MB:Myc盒;TAD:转录激活域;NLS:核定位序列;HLH:螺旋-环-螺旋结构;Zip:拉链结构。研究中发现c-Myc对基因的转录抑制作用还需要甲基化酶对该基因启动子区进行DNA甲基化[9]。下降[14]。c-Myc的过表达会导致细胞周期蛋白A、细胞周期蛋白E以及细胞周期蛋白D2的表达上升...
C-MYC/MYC抗体 英文名称: Anti-C-MYC/MYC Antibody (Clone#OTI1A6) 产品规格: 50μl|100μl|150μl 发货周期: 1～3天 产品价格: 询价 本产品仅可用于科研实验,严禁用于其他非科研用途! 抗体名称Anti-C-MYC/MYC Antibody (Clone#OTI1A6) 指标别名bHLHe39;c Myc;c-Myc;MRTL;MYC;Myc proto oncogene ...