上海玉博生物科技有限公司 主要致力于“c-Myc (D84C12) XP(tm) Rabbit mAb CST 5605S”的生产销售。多年的“c-Myc (D84C12) XP(tm) Rabbit mAb CST 5605S”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深受广大用户信赖。欢迎来电咨询或
最后,对负离子模式下的差异代谢物的贡献度进行VIP计算,发现乳酸对于区分模型组和左归降糖解郁方高剂量组的贡献值最大。 3.4左归降糖解郁方对糖尿病并发抑郁症大鼠海马SIRT1、c-Myc、LDHA蛋白表达的影响 如图5所示,与对照组比较,模型...
Flow cytometric analysis of Jurkat cells using c-Myc (D84C12) Rabbit mAb (Alexa Fluor® 488 Conjugate) (solid line) compared to concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control (Alexa Fluor® 488 Conjugate) #2975 (dashed line). 1/1 Learn more about how...
Therefore, CSIG silencing induced depletion of cells in the S phase and apoptosis in HCC cells. CSIG affects MYC protein expression To clarify how CSIG affects the proliferation and cell cycle of HCC cells, we examined the protein levels of a number of important tumor-related genes, including ...
(T389) (cat. no. 9205) used at 1:2,000, p70 S6 kinase (cat. no. 9202) used at 1:2,000, STAT1 (cat. no. 9172) used at 1:2,000, Rb (cat. no. 9309) used at 1:2,000, Glut1 (cat. no. 12939) used at 1:4,000, and c-Myc (cat. no. 5605) used at 1:2,000. ...
S5c), and both c-Myc KO and p53 knockout (p53 KO) inhibited the cell death, even though the basal survival rate was higher in control cells (Supplementary Fig. S6a, b). In particular, the spheroid culture system, which is more similar to the in vivo condition than to conventional ...
Myc in SW480 cells is a stress condition that promotes this proteolysis. It is of note here that we have used only a single shRNA sequence construct to provide a proof of principle. Further research may identify sequences or combination of sequences with even higher RNAi efficiency. With ...
(single fixation) and then chromatin sonicated to 200–600 bp. ChIP was carried out using antibody against c-Myc (D84C12) (Cell Signaling, cat # 5605S). ChIP DNA was purified using the SimpleChIP®Plus Enzymatic Chromatin IP Kit (Cell signaling, cat #9005). The ChIP-DNA was analyzed...
33,34 Direct targeting of c-MYC is difficult because it’s a disordered protein that lacks binding pockets and is localized in the nucleus.35 Several strategies to inhibit c-Myc include preventing c-Myc translation, decreasing the stability of c-MYC protein, inhibiting the formation of an ...
Data are presented as mean ± S.E.M. *p≤ 0.05, **p≤ 0.01 (Student's t-test). Next, we explored the mechanism whereby YUM70 suppressed c-MYC expression. One possibility is that YUM70 treatment reduced the levels of c-MYC transcripts. To test this, the HNSCC lines described above ...