It has a small and tractable nervous system, which consists of 302 neurons and approximately 5,000 chemical synapses [ 2 ]. Every neuron has been identified, its cell lineage traced and it connectivity patterns mapped [ 2 ]. Many of the C. elegans genes involved in coding its neural ...
the development of each of its 959 somatic cells has been observed (plus 72 more in the adult male); every one of its 302 neurons has been traced. Its entire 100 million base-pair genome has been sequenced. And because human beings share more than a third of the C. elegans genome, we...
C. elegans neurons were thought to be non-spiking until our recent discovery of action potentials in the sensory neuron AWA; however, the extent to which the C. elegans nervous system relies on analog or digital coding is unclear. Here we show that the enteric motor neurons AVL and DVB fir...
以秀丽隐杆线虫(C.elegans)、小鼠及人源传代细胞系等为研究对象,结合临床病例,综合运用分子遗传学、膜片钳电生理、 …mypage.zju.edu.cn|基于280个网页 3. 秀丽线虫 秀丽线虫(C.elegans)中核酸酶(NUC-1)抑制子的遗传筛选Other Titles: Genetic screen of nuc-1 suppressors in C.elegans Aut…oaps.lib.tsing...
在大多数动物神经系统中突出的脉冲神经元将连续输入压缩成数字、再生动作电位,从而有效地长距离传输信息。分级神经元每个时间间隔可以编码多于一比特的信息,但比脉冲神经元对噪声更敏感(Sarpeshkar, 1998)。分级信号允许在神经元的不同部分进行并行计算,甚至脉冲神经元在其树突轴中使用这种多路复用特性(London and ...
C.elegans (Caenorhabditis elegans)is a free-living, transparent nematode (roundworm), about 1 mm in length, which naturally lives in temperate soil environments.C. elegansis a self-fertilizing hermaphrodite that has a temperature sensitive life span. They are also inexpensive to maintain and can ...
C. elegans AWA Olfactory Neurons Fire Calcium-Mediated All-or-None Action Potentials Cell, no. 1 (2018): 57-70.e17 SUMMARY 秀丽隐杆线虫和其他线虫中的神经元被认为缺乏经典动作电位。出乎意料的是,我们观察到膜电位脉冲,具有在电流截断条件下记录的线虫AWA嗅觉神经元中动作电位的定义特征。离子取代实验、...
Differential gene expression specifies the highly diverse cell types that constitute the nervous system. With its sequenced genome and simple, well-defined neuroanatomy, the nematode C. elegans is a useful model system in which to correlate gene expressi
elegans has attracted tremendous attention primarily because of its simple nervous system with 302 neurons. Data generated by comprehensive reconstruction and other efforts were initially deposited to and retrieved from ACeDB. More recently, Wormbase was created, which allows users to access data ...