UHPLC Choose Specialty July 7, 2020 Article Sponsored Content - EU In this white paper we discuss the importance of correct mobile phase buffer selection and pH control in LC and LC–MS method development. Application Notes: LC Enhanced separation of plasmid isoforms via HIC ...
rapid and sensitive RP-HPLC IIR method for the determination of acetic and trifluoroacetic acids (AA and TFA) in synthetic peptides.Separation was carried out using a C_(18) column and a mobile phase consisting of 4.5 mmol L~(-1) tetra-n-butylammonium hydrogen sulfate (TBAHS),as IIR,in ...
This process should be suitable for generating a large number of formulations for stability testing with limited drug substance. This work will need to support the selection of a formulation for in vivo safety studies, including the earliest human trials. This imposes further constraints with regard...
This relationship can be utilized in the future for the optimization of solute retention in RP-HPLC systems with methanol-phosphate buffer mobile phases.doi:10.1007/BF02279482N. DimovaT. KowalskaN. DimovSpringer-VerlagChromatographiaw22x N. Dimova, T. Kowalska, N. Dimov, Physicochemical mod- ...