Radiation-induced fibrosis (RIF) is a late side effect from radiation therapy, occurring 4–12 months after radiation therapy, and can be seen in approximately 5–30% of patients receiving radiation therapy to the breast or chest wall. Typical effects of RIF include decreased tissue compliance, ...
Background Radiation fibrosis is not easily measurable although clinical scores have been developed for this purpose. Biomarkers present an alternative more objective approach to quantification, and estimation in blood provides accessible samples. We investigated if blood cytokines could be used to measure...
Background Since the introduction of breast-conserving treatment, various radiation doses after lumpectomy have been used. In a phase 3 randomised controlled trial, we investigated the effect of a radiation boost of 16 Gy on overall survival, local control, and fibrosis for patients with stage I...
Radiation therapy.In some cases, it can cause pulmonary fibrosis, which scars your lung tissue. You might notice: Dry cough Trouble breathing Chest pain These symptoms typically show up 2-3 months after your treatment ends. It may first look likepneumonia, butantibioticswon’t help. Your doctor...
Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boos... To investigate the long-term impact of a boost radiation dose of 16 Gy on local control, fibrosis, and overall survival for patients...
Implant-based reconstructions are increasingly utilized following mastectomy in the prevention and treatment of breast cancer. However, these implants are associated with a high rate of infection, which is a major complication that can lead to implant removal, delay in adjuvant radiation and chemotherapy...
Physician-rated cosmetic outcomes were good/excellent, and chronic toxicities were grade 1 to 2 (fibrosis, hyperpigmentation) in patients receiving preoperative radiation only. Evidence of dose-dependent changes in vascular permeability, cell density, and expression of genes regulating immunity and cell ...
Two cases are presented of subclavian and axillary vein thrombosis in patients with carcinoma of the breast treated by radiotherapy and at least 2 years of therapy with tamoxifen. We suggest that radiation fibrosis may have been the major aetiological factor but that the treatment with tamoxifen mig...
Dr. Yallapu: My work interface of nanomedicine and cancer immunology is poised to make significant contributions to the advancement of cancer therapies. By developing innovative MUC13 antibody-drug conjugate systems, it addresses one of the biggest challenges in cancer treatment. More importantly, our...
One developed mastitis under treatment requiring oral and IV antibiotics. Another received oral antibiotics for 6 weeks following formation of a draining sinus tract with contracture and painless fibrosis. Three others reported slight to moderate firmness. Four noted mild hyperpigmentation, but none ...