Subclone composition can vary over space (within the same tumor mass or across metastatic sites) and time (sequential samples). All subclones in a cancer are by definition genetically related, having arisen from a single common ancestor, but individual subclones are distinguished by the existence ...
If it's unclear whether a mass is due to a fluid-filled abscess or to a solid mass such as a tumor, you may get a test such as an ultrasound. Anultrasoundmay also tell whether you have simple mastitis, or an abscess deep in the breast. This noninvasive test allows your doctor to ...
a: Heart, b: Liver, c: Spleen, d: Lung, e: Kidney, f: Tumor. (D) Semi-quantification distribution of free Dir or Dir/HA-b-PCDA NPs in tumors and major organs at 48 h post-administration. (E) The permeation of free Dir or Dir/HA-b-PCDA NPs in the whole tumor mass, scale ...
TMT-based mass spectrometry (MS)-quantified protein data have been submitted into iProX (https://www.iprox.cn) under accession codes IPX0006535000. Human Primary Cell Atlas data are obtained from the celldex package (v1.11; https://github.com/LTLA/celldex). The TCGA, METABRIC and CPTAC ...
to the host (for example, sex20, age21and body mass index) or the environment (for example, tobacco, alcohol and commensal microbiota). It remains unclear to what extent anti-tumor immunity is driven by the tumor, by the host and/or by the interaction between the host and the tumor. ...
And on that initial exam — by the initial ultrasound, it was about a 2.3-cm left breast mass. She had a core biopsy that confirmed that this was invasive ductal cancer, mucinous and micropapillary features, intermediate grade, positive LVI, strongly ER-positive but PR-negative and HER2-...
Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues. Breast Cancer Res Treat. 2019;173(3):667–77. Article CAS PubMed Google Scholar Subbaramaiah K, Howe LR, Bhardwaj P, Du B, Gravaghi C, Yantiss RK, et...
Finally, the levels of biotinylated proteins were determined by mass spectrometry in collaboration with the BioProfile (Shanghai, China). GST pull-down assay The GST pull-down assay was performed as previously described [26]. Briefly, the pGEX-6P-1 plasmid encoding GST, full-length GST-NONO ...
Epithelial-mesenchymal transition (EMT) inducing transcription factor TWIST1 plays a vital role in cancer metastasis. How the tumor-suppressive E3 ligase, speckle-type POZ protein (SPOP), regulates TWIST1 in breast cancer remains unknown. In this study,
Dhungel, N., Carneiro, G. & Bradley, A. P. The Automated Learning of Deep Features for Breast Mass Classification from Mammograms. In Ourselin, S., Joskowicz, L., Sabuncu, M. R., Unal, G. & Wells, W. (eds)Medical Image Computing and Computer-Assisted Intervention – MICCAI 2016: ...