3c). To gain further insights into the regulatory roles of MIIP in AZGP1 secretion, we conducted tandem affinity purification and mass spectrometry analysis to identify proteins that associate with MIIP. The results revealed a potential direct interaction between MIIP and AZGP1 (Additional file 1...
As a result, the PTEN‐induced putative kinase 1 (PINK1)/Parkin signaling pathway was activated, accompanied by excessive mitophagy and reduced mitochondrial mass in cells. We also revealed that kaempferol‐induced lethal mitophagy contributed to inhibiting breast precancerous lesion growth in vitro ...
Reports on the misdirected attention from known causes of cancer due to wrong information in the United States. Declining mortality rates for most cancers in people under 55 years; Improvements in cancer-screening methods; Attribution of the increase in breast and prostate cancer rates; Relation of...
a, LILRB3 knockout in normal cells retained RasV12 cell in the epithelial monolayer, and the remaining RasV12 cells formed tumor like cell mass in vitro. Schematic of in vitro pile-up colony formation assay (top) and representative XY images of fluorescence staining (bottom) are shown. HaCa...
Mass spectrometric analysis of high-mobility group proteins and their post-translational modifications in normal and cancerous human breast tissues. High-mobility group (HMG) A1 proteins including HMGA1a and HMGA1b are chromosomal proteins that function in a variety of cellular processes such as cell...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook noncancerous (ˌnɒnˈkænsərəs) adj 1.(Medicine) (of tissue) not cancerous, benign 2.(Medicine) (of a patient) not having cancer ...
Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis Distinguishing tumor from normal glandular breast tissue is an important step in breast-conserving surgery. Because this distinction can be challenging in ... D Calligaris,D Caragacianu,X Liu,.....
Tests in 91 human patients have shown the tool's diagnoses were extremely accurate, and may be reliable enough to begin widespread use in operating rooms. The iKnife uses mass spectrometry (质谱法) to examine the surgical smoke given off by tissue, informing the surgeon in three seconds as ...
"This suggests to us that CoQ10 could be an effective adjuvant anti-tumor agent in breast carcinomas," said Indushekhar Persaud, research associate in the Department of Dermatology and Cutaneous Surgery at the Miller School of Medicine." ...
The target protein bands were subjected to in-gel digestion with trypsin and finally analyzed using an ESI-ion trap mass spectrometer.A total of 50 differentially expressed proteins in colonic cancerous and normal tissues were identified.Many of the identified proteins have been reported to be ...