Immune approaches to the treatment of breast cancer, around the corner? Carmen Criscitiello, Angela Esposito, Lucia Gelao, Luca Fumagalli… Article:204 Download PDF (602KB) View Article Review Clinical development of mTOR inhibitors in breast cancer Cecile Vicier, Maria Vittoria Dieci, Monica...
https://www.cancer.gov/types/breast/hp/breast-treatment-pdq 16. Alvidrez J, Castille D, Laude-Sharp M, Rosario A, Tabor D. The National Institute on Minority Health and health disparities research framework. Am J Public Health. 2019;109(S1):S16-S20. doi:10.2105/...
This chapter is a general overview briefly describing the treatment of breast cancer, intended to aid understanding of the various cases that will be mentioned in this book. Treatment for breast cancer includes local and systemic treatments, which are divided into pre-surgery neoadjuvant therapy and ...
The thought-provoking SONIA trial showed that patients with hormone receptor-positive, HER2-negative advanced-stage breast cancer receiving deferred (second-line) versus first-line cyclin dependent-kinase (CDK) 4/6 inhibitors have noninferior progression-free survival after second-line treatment; such ...
Organoid culture using microfluidic tumor-on-a-chip model can improve reproducibility and promote the standardization of protocols (Fig. 1C). Ayuso et al. (2021) created a microfluidic tumor-on-a-chip model that compromised NK cell cytotoxic capacity. In this microfluidic device, breast cancer ...
The protocol and breast support can be added straightforwardly to standard abdominal or thoracic scans, enabling breast density to be measured routinely as part of standardised acquisition protocols. P15 A review of the direct access to mammogram program introduced in Ireland for women over 35 years...
70-Gene Prognosis and 80-Gene Subtype Assignments MammaPrint and BluePrint assays were performed according to standard protocols and have been previously described.20,21 These tests are based on microarray gene expression analysis of RNA extracted from FFPE breast tumor tissue and use custom-designed ...
A patent application has been filed on aspects of the described work, entitled ‘Methods of treatment based upon molecular characterization of breast cancer’ (C. Curtis, C. Caldas, J.A.S. and O.M.R.). Additional information Publisher’s note: Springer Nature remains neutral with regard to...
All animal studies were performed in accordance with protocols approved by the Institutional Animal Care and Use Committee at Northeastern University. An orthotopic xenograft model of human TNBC was established via injection of 1 × 106 MDA-MB-231-LUC-D3H2LN cells (cultured in DMEM with 10%...
Breast cancer neoadjuvant chemotherapy (NAC) consists of the administration of cytotoxic and targeted drugs prior to breast surgery, with the objective of reducing the tumor burden to allow breast conservation. NAC also aims to improve long-term treatment outcomes such as disease-free and overall sur...