breast cancer is the most prevalent cancer in females. Statistically, 95% of breast cancer are categorized as adenocarcinomas, and 55% of all patients may go into invasive phases; however, it can be successfully treated in approximately 70–80% of cases if diagnosed in the nascent stages. The...
To date, there have not been great breakthroughs in immunotherapy for HER2 positive breast cancer (HPBC). This study aimed to build a risk model that might contribute to predicting prognosis and discriminating the immune landscape in patients with HPBC. We analyzed the tumor immune profile of HP...
Venn diagram showing beliefs of market women about breast cancer.Kelechi, Elizabeth OladimejiJoyce, M. TsokaGwegweniFranklin, C. IgbodekweMary, TwomeyChristopher, AkoloHadiza, Sabuwa BalarabeOlayinka, AtilolaOluwole, JegedeOlanrewaju, Oladimeji
EMT is one of the critical mechanisms in breast cancer metastasis [5, 40]. Abnormal regulation of EGFR signaling in tumors usually leads to changes in cell proliferation and adhesion, increasing cell aggressiveness and motility, which are hallmarks of EMT and the initial stages of tumorigenesis [...
Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study. Breast Cancer Res. 2014;16(1):R18. Article PubMed PubMed Central Google Scholar Kelsey JL, Gammon MD, John EM. Reproductive factors and breast cancer. EpidemiolRev. 1993;15(1):36–47. CAS Google ...
Results A total of 424 survivors of stages 0 to III breast cancer who had completed cancer treatments at least 12 months previously were screened, and 288 were randomized, with 270 receiving relaxing acupressure (n = 94), stimulating acupressure (n = 90), or usual care (n = ...
Understanding the mechanisms that enable cancer cells to metastasize is essential in preventing cancer progression. Here we examine the metabolic adaptations of metastasis-initiating cells (MICs) in female breast cancer and how those shape their metastatic phenotype. We find that endogenous MICs depend ...
Most studies enrolled patients who had been diagnosed with breast cancer stages II and III (n = 17), but some studies also recruited stage I patients (n = 8) and a few studies recruited non-metastatic patients (n = 3). According to these studies, the percentage of patients...
Cancer incidence escalates exponentially with advancing age; however, the underlying mechanism remains unclear. In this study, we build a chronological molecular clock at single-cell transcription level with a mammary stem cell-enriched population to dep
A flow diagram depicting a step-wise text mining and machine learning framework for the retrieval of blood profile data against breast cancer metastasis is depicted in Fig. 2a. A pie chart was used to represent the percentage of medical records that matched against biopsy, lymph node, and ...