“Doc, my wife’s breast cancer has come back and spread to her bones”. My friend’s eyes filled with tears when he spoke those chilling words. Like millions of other cancer patients, his wife had been treated successfully. Cancer recurrence is never a good sign, but it doesn’t mean...
Are kidney cancer and breast cancer related? Can ovarian cancer spread to the kidney? Can kidney cancer spread to the bladder? Can kidney cancer spread to the colon? Can kidney cancer spread to the lungs? Can kidney cancer spread to the bones?
Cancer is a type of abnormal growth where cells multiply profusely, are abnormal in structure and invade surrounding tissue. It can arise from any tissue that makes up the breast but more commonly arises from the glandular epithelium lining the ducts. The transition from normal to cancerous cells...
Breast cancer frequently metastasizes to the skeleton, interrupting the normal bone remodeling process and causing bone degradation. Osteolytic lesions are the end result of osteoclast activity; however, osteoclast differentiation and activation are medi
Local therapies, such as surgery and radiation, are used to remove or destroy breast cancer in a specific area. If the breast cancer has spread to other parts of the body, local therapy may also be used to control cancer in those specific areas, such as in the lung or bone. ...
RANKL and RANK can be both expressed in triple-negative breast cancer (TNBC) [82]. Interestingly, dual expression of RANKL and RANK correlates with a poor prognosis in TNBC patients. In fact, TNBC patients expressing both RANKL and RANK show significantly worse relapse-free survival and overall...
This rare cancer begins in blood or lymph vessels in the breast tissue or in the skin of the breast. It can occur after radiation therapy to an area. Metastatic breast cancer. This is cancer that has spread to another body part, like your brain, bones, or lungs. Breast cancer epidemiolog...
Freezing breast tumors may help stop the cancer to spread, according to a study by Univ. of Mich. The researchers said the rapid freezing method was effective in mice, and when the tumors were frozen rapidly in less than 30 seconds, the survival rate of mice was better. Cryoablation makes...
cancer. Other common sites of breast cancer metastasis are the brain, the bones, and theliver. Cancers that have spread only into the lymph nodes under the arm are still curable. Those that spread to distant lymph nodes or other organs are not usually curable with available treatments today....
Current treatments are largely palliative and new therapies that specifically prevent the spread of breast cancer to bone are urgently required. Little is known, however, about the molecular determinants that regulate homing of breast cancer cells to bone. Integrins are dimeric adhesion receptors that ...