Breast cancers are ER-positive, HER2-positive, or triple negative. The type of breast cancer you have determines the type of medication you take. Learn more from experts at WebMD.
In this report, we present the case of a female patient with relapsed and metastatic breast cancer, whose histology transformed from initially triplenegative to Luminal-B type (HER2 positive) (i.e., ER, PR, and HER2 positive). She underwent systematic chemotherapy, ta...
Intravenous liposomal irinotecan in metastatic triple-negative breast cancer after ≥ 2 prior lines of chemotherapy: a phase Ib study Cytotoxic chemotherapy remains the standard treatment for triple negative breast cancer (TNBC), an aggressive subtype of breast cancer associated with poor prognosis. Her...
The long-sought discovery of HER2 as an actionable and highly sensitive therapeutic target was a major breakthrough for the treatment of highly aggressive HER2-positive breast cancer, leading to approval of the first HER2-targeted drug — the monoclonal antibody trastuzumab — almost 25 years ago....
Breast cancer is a heterogeneous disease, and within the HER-2 positive subtype this is highly exemplified by the presence of substantial phenotypical and clinical heterogeneity, mostly related to hormonal receptor (HR) expression. It is well known how HER-2 positivity is commonly associated with ...
Estrogen receptor-positive, progesterone receptor-negative, and human epidermal growth factor receptor 2 (HER2)-negative (ER+PR-HER2-) breast cancer comprise a special type of breast cancer that constitutes ~10% of all breast cancer patients. ER+PR-HER2- tumor benefits less from endocrine therapy...
areferential meaning 参考意思[translate] amonotone 单调[translate] aI have no one again in my family i'm the only person 我再有没人在我家i'm唯一的人[translate] anegative breast cancer: A comparison between younger 消极乳腺癌: 比较在更加年轻之间[translate]...
[15]Datopotamab deruxtecan (Dato-DXd) vs chemotherapy (CT) in previously treated inoperable or metastatic hormone receptor-positive, HER2-negative (HR+/HER2–) breast cancer (BC): Patient-reported outcomes (PROs) from the TROPION-Breast01 study.2024 ASCO 1006 ...
This chapter provides an overview of the procedures and technical aspects of bone scintigraphy, clinical application in breast cancer, pitfalls and problems encountered and their solutions, and potential advances. In the case of bone scintigraphy (BS), the visualized metabolic process is the osteoblasti...
Fig. 5: The visualization based on Gradient-weighted Class Activation Mapping (Grad-CAM) method of the proposed model in predicting 4-category molecular subtypes of breast cancer. Case a–d indicate the category of Luminal A, Luminal B, HER2-enriched and Triple-negative, respectively. MG mammogr...