Molecular subtypes in breast cancer evaluation and management: divide and conquer. Cancer Invest. 2008; 26 :1–10. doi: 10.1080/07357900701784238. [ PubMed ] [ Cross Ref ]Peppercorn J, Perou CM, Carey LA. Molecular subtypes in breast cancer evaluation and management: divide and con...
Conclusions Tumour molecular subtypes strongly impact incidence, kinetics and prognosis of CNS metastases in MBC patients. Clinical trial registration NCT03275311.Similar content being viewed by others HER2 expression and genOmic characterization of rESected brain metastases from colorectal cancer: the HEROES...
Breast cancerMolecular subtypesProteomicsBiomarkersReviewBreast cancer is traditionally considered as a heterogeneous disease. Molecular profiling of breast cancer by... SW Lam,CR Jimenez,E Boven - 《Cancer Treatment Reviews》 被引量: 87发表: 2014年 Molecular characterization and targeted therapeutic approa...
Statistical analysis of the methylation microarray data revealed extensive DNA-methylation changes between tumor and adjacent tissue (Figure 1, Table S2 in Additional file 2) and concurrence of some of these DNA-methylation changes with particular breast cancer molecular subtypes and tumor morphologies. ...
The results of different models in terms of the evaluation metrics for predicting 4-category molecular subtypes of breast cancer in the test cohort (n = 672) are displayed in Table 2. The Multi-ResNet50 model had an accuracy of 84.4%, precision of 83.7%, recall of 81.3%, F1-score...
Compared to female breast cancer, the incidence of male breast cancer has risen in recent years, and the relationship between molecular subtype and clinical behavior has rarely been studied. In this study, we examined the molecular subtypes of male breast cancers based on the expression profile of...
Breast cancer incidence has been on the rise significantly in the Asian population, occurring at an earlier age and a later stage. The potential predictive value of molecular subtypes, biomarkers, and genetic variations has not been deeply explored in th
To the best of our knowledge, this study is the first to report on using a combination of clinical history, radiologist-defined image feature extraction from both mammography and MRI, and decision tree-based machine learning to support the prediction of breast cancer molecular subtypes in a multi...
Indeed, HER-2 positive breast cancer heterogeneity has been suggested to underlie the variability of response not only to endocrine treatments, but also to HER-2 blocking agents. Among HER-2 positive tumors, HR status probably defines two distinct subtypes, with dissimilar clinical behavior and ...
Breast cancer molecular subtypes respond differently to preoperativ e chemotherapy. Clin Cancer Res. 2005;11(16):5678–85. https://doi.org/10.1158/1078-0432.CCR-04-2421. Article PubMed CAS Google Scholar Lee YM, Oh MH, Go JH, Han K, Choi SY. Molecular subtypes of triple-negative ...