In addition, we discuss the use of the Formalin-Fixed, Paraffin-Embedded (FFPE) tissue as an invaluable source for breast cancer biomarker discovery and validation, and the potential use of circulating miRNAs in blood for early breast cancer detection. We envision the potential use of miRNAs in...
Breast cancer is considered as a heterogeneous disease comprising various types of neoplasms, which involves different profile changes in both mRNA and micro-RNA (miRNA) expression. Extensive studies on mRNA expression in breast tumor have yielded some very interesting findings, some of which have bee...
MicroRNA (miRNA) can be used as a biomarker to predict which patients are likely to face breast cancer recurrence and mortality, according to study results published online ahead of print in theJournal of the American College of Surgeons (JACS). While long-term outcomes have improved forpatients...
prognostic biomarker for breast cancer Cailu Song1,*, Lijuan Zhang1,*, Jin Wang1,*, Zhongying Huang2, Xing Li1, Mingqing Wu3, Shuaijie Li1, Hailin Tang1 & Xiaoming Xie1 More sensitive and effective diagnostic markers for the detection of breast cancer are urgently ...
This review focuses on miRNAs that have prognostic, diagnostic or predictive potential in breast cancer as well as the possible challenges in the translation of such observations to the clinic. 展开 关键词: biomarkers prognostic biomarker clinical applications breast cancer diagnostic biomarker miRNA ...
It has been shown that specific miRNA, such as miR-195 and let-7a, may play a role as a potential diagnostic tool and a new biomarker for both detecting non-invasive, early breast cancer as well as monitoring treatment effectiveness [36, 37]. Furthermore, other studies have revealed miRNA...
Breast cancer miRNATerms of use Updates Download Upload Home KM plotterPlot options 1. Select miRNA ID: 2. Select dataset: Compare METABRIC (n=1262) TCGA (n=1078) GSE40267 (n=181) GSE19783 (n=101) Survival options Survival Split patients by Auto select best cutoff Trichotom...
MIR196A is a biomarker of breast cancer progression To further explore the expression ofMIR196Ain breast cancer, we utilised expression data from the METABRIC cohort of breast tumours.40,41Expression analysis of this miRNA indicate that it is significantly over-expressed in breast tumours compared ...
Cancer Cell International (2021) The emerging role of exosomal miRNAs as a diagnostic and therapeutic biomarker in Mycobacterium tuberculosis infection Rasoul Mirzaei Sajad Babakhani Rasoul Yousefimashouf Molecular Medicine (2021) A cancer stem cell-like phenotype is associated with miR-10b expression...
The biomarker potential for exosomes holds huge promise and may revolutionise the way in which we diagnose and manage breast cancer. These nanovesicles may be isolated from a variety of bodily fluids, including serum, and their miRNA content has been shown to reflect that of the parent breast ...