Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in ER- breast cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene ...
Breast cancer starts as a local disease, but it can metastasize to the lymph nodes and distant organs. At primary diagnosis, prognostic markers are used to assess whether the transition to systemic disease is likely to have occurred. The prevailing model of metastasis reflects this view — it ...
Presented at: 27th Annual San Antonio Breast Cancer Symposium (SABCS); December 8-11, 2004; San Antonio, TX. Abstract 1069. Serafini AN. Therapy of metastatic bone pain. J Nucl Med 2001, 42:895-906. About this Chapter Title The diagnosis and treatment of bone metastases in breast cancer...
To investigate any rational relation between breast cancer metastasis to various organs, a comprehensive comparison ran among the common upregulated hub genes designated to have a critical role in primary and bone-metastatic breast cancer and the hub genes which were responsible for breast cancer metas...
Breast cancer is the most common malignant neoplasm in the female population. However, stomach is a rare site for metastasis, and can show up many years after initial diagnosis and treatment of the primary tumor. Analyze a case series of this tumor and propose measures that can diagnose it wi...
1. Understanding Breast Cancer 1.1 Definition Breast cancer is defined as the uncontrolled growth of abnormal cells in the breast tissue. These cells have the potential to invade surrounding tissues and spread to other parts of the body, a process known as metastasis. 1.2 Risk Factors Several ris...
Metastatic disease of the breast is a heterogeneous disease and ranges from a solitarymetastasisto diffuse disease within multiple organs. Despite the medical advances in the detection and diagnosis of breast cancer at an early stage, approximately 30% of patients with early-stage breast cance...
Here, we discuss the molecular basis of breast cancer metastasis and the challenges in personalization of treatment. The instability of metastatic tumors remains a leading obstacle to personalization, because information from a patient's primary tumor may not accurately reflect the metastasis, and one ...
U.S. researchers identify gene in breast cancer pathway (File photo) The findings could help predict whether breast tumors will metastasize and also reveal potential drug targets for preventing metastasis, the university announced here on Tuesday. ...
Lastly, we aimed to evaluate the significance of the two genome-wide significant SNPs using an independent set of 293 breast cancer patients with metastatic primary breast cancer at diagnosis from the SNPs to Risk of Metastasis (StoRM) study19. All patients were diagnosed in France from March 20...