Aetna considers germline multigene panel testing for moderate to high-penetrance breast and/or epithelial ovarian cancer susceptibility genes (must include BRCA1, BRCA2, CDH1, MLH1, MSH2, MSH6, PALB2, PTEN, STK11, TP53) and full duplication and deletion analysis (i.e., detection of large ge...
Also, screening for some cancers, including colorectal and cervical cancer, can be initially conducted via home testing, and there is some evidence that such testing increased during the pandemic.9,27 More widespread recognition of the slow recovery from pandemic-related deficits in cancer screening ...
Moreover, these researchers stated that further investigation with standardized sensory testing methods and patient-reported outcome tools is needed to support neurotization as a standard of care (SOC) in breast reconstruction surgery.Harish et al (2022) stated that as breast-conserving procedures becom...
Trastuzumab resistance has been becoming a major obstacle for treatment of HER-2-positive breast cancer patients. Increasing evidence suggests that mesenchymal stem cells (MSCs) play critical roles during the formation of drug resistance, however, the underlying mechanism is not well known. In this ...
Breast cancer cells line MCF10A, MCF-7, MDA-MB-468, BT-483 and HCC2218 were obtained from American Type Culture Collection (ATCC, Manassas, VA, USA). Upon thawing and passaging, cells were used until passage number 20. Mycoplasma testing was done every other month, using the MycoAlert ...
Sepiapterin, also known as PTC923 and CNSA-001, is a synthetic form of endogenous sepiapterin being developed as a novel oral treatment for phenylketonuria
Tumor biopsies have been and currently are the keystone for biomarker testing [1]. However, some limitations of tumor biopsies are still significant, such as difficulties in obtaining tissue samples, the invasiveness of the process or tumor heterogeneity, which might compromise the efficacy of targete...
CPB 0227 - Breast and Ovarian Cancer Susceptibility Gene Testing, Prophylactic Mastectomy, and Prophylactic Oophorectomy CPB 0615 - Gender Reassignment Surgery Table: Applicable CPT / HCPCS / ICD-10 Codes CPT codes covered if selection criteria are met: ...
miRNA analysis of breast ductal fluid for the detection of breast cancer. Related Policies CPB 0227 - BRCA Testing, Prophylactic Mastectomy, and Prophylactic Oophorectomy. Table: CPT Codes / HCPCS Codes / ICD-10 Codes Information in the [brackets] below has been added for clarification purposes....
Combination therapy demonstrated a promising strategy to target hard-to-treat cancers and sensitize cancer cells to conventional anti-cancer drugs such as doxorubicin. This study aimed to establish molecular profiling and therapeutic efficacy assessment of chloroquine and/or tioconazole (TIC) combination ...