The Breast Cancer Index (BCI) is a gene expression assay that provides both a prognostic risk of late distant recurrence in addition to a yes/no prediction of benefit from receiving extended endocrine therapy. To date, no studies have examined the relationship between race and BCI score. This ...
NP: Normal persons; BCP: Breast cancer patients CONCLUSIONS This study investigates discriminating tongue features to distinguish between BCPs and normal people, and establishes differentiating index to facilitate the non-invasive detection of BC. The Mann–Whitney test showed that the amount of tongue...
PURPOSE: Previous results from the TransATAC study demonstrated that both the Breast Cancer Index (BCI) and the OncotypeDX Recurrence Score (RS) added significant prognostic information to clinicopathologic factors over a 10-year period. Here, we examined cross-stratification between BCI and RS to ...
Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From... Background: Brain metastases are a common sequelae of breast cancer. Survival varies widely based on diagnosis-specific prognostic factors (...
Abbreviations: PRS, polygenic risk score; CI, confidence interval. a The Harrell’s C-index was obtained by the STATA stcox postestimation command “estat concordance,” using time since first breast cancer on the timescale without taking delayed entry (prevalent cases) into account. We did not...
Gene signatures include the Oncotype Dx recurrence score (Genomic Health), PAM50-based Prosigna risk of recurrence score (NanoString), Breast Cancer Index (bioTheranostics), and EPclin (EndoPredict clinical score [Myriad Genetics]). Cutoffs for risk of recurrence score were trained separately in ...
Abbreviations: CI, confidence interval; NPI, Nottingham Prognostic Index; PREDICT (www.predict.nhs.uk); SNAP (www.CancerMath.net). Hazard ratios with P values < 0.05 are marked in bold. Figure 2. The prognostic performance of the BCT score compared with that of clinical variables...
Conclusion: The prognostic score and predictive index are useful methods to estimate the risk of LRR in breast cancer patients after mastectomy and for estimating the potential benefits of PMRT. These models provide additional information criteria for selection of patients for PMRT, compared with the...
Purpose: Survival of metastatic breast cancer patient remains unknown and varies greatly from person to person. Thus, we aimed to construct a nomogram to quantify the survival probability of patients with metastatic breast cancer (MBC). Materials and methods: We had included 793 MBC patients and ...
Aggressive breast cancers portend a poor prognosis, but current polygenic risk scores (PRSs) for breast cancer do not reliably predict aggressive cancers. Aggressiveness can be effectively recapitulated using tumor gene expression profiling. Thus, we sou