Breast Cancer Index re-stratifies 21-gene assay risk groups for late distant recurrence and extended endocrine therapy benefit: Results from the BCI Registry Study.doi:10.1200/JCO.2024.42.16_suppl.52910529#Background:Patients with hormone receptor-positive (HR+) breast cancer face a prolonged risk...
RESULTS: There were 1,960,682 incident cases and 611,625 deaths of breast cancer globally in 2017, contributing to 17,708,600 DALYs. The age-standardized incidence rates (ASIRs) increased between 1990 and 2017, while the age-standardized mortality rates and DALY rates decreased. The correspondi...
The tumour immune microenvironment is shaped by the crosstalk between cancer cells, immune cells, fibroblasts, endothelial cells and other stromal components. Although the immune tumour microenvironment (TME) serves as a source of therapeutic targets, it
more mature and memory B cell characteristics. These TNBC-infiltrated memory B cells had higher clonality and extensiveIGHCSR and SHMs, which likely happened within tumors and experienced tumor antigen recognition. Our results also confirmed the existence of functionally active germinal centers in TNBC ...
Abstract S1-05: a randomized, double-blinded, placebo-controlled clinical trial of extended adjuvant endocrine therapy (tx) with letrozole (L) in postmenopausal women with hormone-receptor (+) breast cancer (BC) who have completed previous adjuvant tx with an aromatase inhibitor (AI): results ...
breast cancer survival: Results from the Nurses’ Health Studies Renée T Fortner, JNCI Cancer Spectrum, 2022 Physical Activity Before, During, and After Chemotherapy for High-Risk Breast Cancer: Relationships With Survival Rikki A Cannioto, JNCI: Journal of the National Cancer Institute, 2020 In...
Ki-67 represents cell proliferation and is a recognized risk factor in breast cancer patients [28, 29]. Our study show that patients had a shorter RFS with high pathologic T stage after NAC, which suggest that lesions with high proliferative capacity may have worse outcomes. The results are ...
Research collaboration:Breast Cancer Association Consortium (BCAC) is a research collaboration whose article contributions are accrued to itsparticipating partner institutions. Return to institution outputs 2024 Research Leaders The Nature Index 2024 Research Leaders — previously known...
Reprogrammed glucose metabolism as a result of increased glycolysis and glucose uptake is a hallmark of cancer. Here we show that cancer cells can suppress glucose uptake by non-tumour cells in the premetastatic niche, by secreting vesicles that carry hi
Explore and run machine learning code with Kaggle Notebooks | Using data from Breast Cancer Wisconsin (Diagnostic) Data Set