Study participant Danielle Lee couldn't agree more. Two years ago, the then 30-year-old mother of a toddler and eight-month-old was coping with a diagnosis that her breast cancer had spread to her spine. The results of the new biopsy confirmed that there was no cancer in her spine. ...
Mutations inESR1, which encodes estrogen receptor-α (ERα), drive resistance to approved endocrine therapies in breast cancer. We studied the molecular response to the investigational ERα antagonist and degrader, giredestrant, in preclinical models and biopsy samples. We found that long-term inh...
Open excisional biopsy.This is surgery to remove an entire lump. The tissue is then studied under a microscope. If your doctor takes a section of normal breast tissue all the way around a lump (called alumpectomy), the biopsy is also considered abreast cancer treatment. In this technique, ...
single breast biopsy slide for each case, we found an overall diagnostic concordance rate of 75.3%, with a high level of agreement between the pathologists’ and the consensus-derived reference diagnosis for invasive breast cancer, and a substantially lower level of agreement for DCIS and atypia....
PD-L1 expression is known to predict the benefits of immune checkpoint inhibitor therapy for triple-negative breast cancer (TNBC). We examined whether the PD-L1 expression evaluated in biopsy specimens accurately reflects its expression in the whole tumor. Immunohistochemistry was ...
The first results of aspiration biopsy cytology (ABC) for 2, 492 women with breast diseases who visited the breast clinic of Nagano Cancer Center on an out-patient basis, during the last 13 years and 3 months, were analyzed retrospectively. The class V, IV rate for 453 malign breast diseas...
"Because of that score, I was sent to get an MRI, which led to an ultrasound, which then led to a biopsy," she explained. "The biopsy showed I had Luminal B cancer in both breasts. Luminal B is an aggressive, fast moving cancer." She underwent a double mastectomy 30 days after the...
Results Factors affecting the engraftment success rates of primary breast cancer The clinicopathological characteristics of the primary breast cancer patient population, including both chemo-naive and NAC groups, in relation to the PDX engraftment are summarized in Table 1, and the detailed PDX engraftmen...
Most breast cancer deaths are due to cancer that's spread elsewhere, and the cancer typically first spreads to an armpit lymph node, explained lead researcher Dr. Basak Dogan, director of breast imaging research at UT Southwestern Medical Center. ...
P056: Post-biopsy cases of breast cancer where localisation is not possible - A clinical dilemmadoi:10.1016/j.ejso.2020.03.095Aditi RajgopalCatherine TaitAlison WaterworthBaek KimBrian HoganEuropean Journal of Surgical Oncology