Cancer stagingis the process of determining how muchcanceris within the body (tumor size) and if it has spread. Forbreast cancer, this might take the form of clinical (pre-surgical) staging or pathologic (surgical) staging. Breast cancer is classified by stages. There are five stages of bre...
Biopsy results: one B1, ten B2, one B3 and four B5 (1% of cohort). Of the four malignancies diagnosed, two were in the symptomatic breast with two in the contralateral breast. The women diagnosed ranged from 51 to 80 years old. Out of 372, 63 (16.9%) of the GP referrals did not...
A nomogram was developed based on the results of multivariate regression analysis from the training group. Discrimination, calibration and clinical usefulness of the nomogram for predicting breast cancer were assessed in the validation group. The radiomics score included 9 selected radiomics features. The...
(in days) between initial consultation and the date of biopsy. The odds ratios were estimated from a generalized linear mixed model, adjusted by age, number of comorbid conditions, marital status, size of residence, cancer stage, estrogen receptor/progesterone receptor status, tumor size, nodal ...
classified as discordant. As breast cancer subtype is known to be the main determinant of tumor biology (notably tumor grade and proliferation), immune infiltration, response to anti-cancer agents and, ultimately, oncologic outcomes, we displayed the results of the clinical section of the paper acc...
METHODS: Fifty-eight male breast cancer patients were treated at the HUCH during 1981-2006. Data on risk factors, tumor characteristics, clinical presentation, treatment and survival were obtained by chart review. RESULTS: Presentation occurred at a median age of 63 years, most often due to a ...
Sentinel lymph node biopsy (SLNB) has become the mainstay of axillary surgical staging in breast cancer patients with clinically negative (cN0) axillary lymph nodes (ALNs); it results in less morbidity than axillary lymph node dissection (ALND) [1]. The landmark ACOSOG Z0011 trial [2, 3] ...
DNA damage response (DDR) deficiency has been one of the emerging targets in treating breast cancer in recent years. On the one hand, DDR coordinates cell cycle and signal transduction, whose dysfunction may lead to cell apoptosis, genomic instability, a
one inherited from each parent. A woman who has received one defective BRCA1 or BRCA2 gene from one parent and a healthy gene from the other is called a carrier of the defective BRCA gene. Even though only one healthy BRCA1 or BRCA2 gene is needed to help prevent cancerous growth of ...
Also, the authors stated that they did not have data on the number of breast biopsies so all who had had a breast biopsy were assumed to have had only one biopsy. Unfortunately the numbers given for participants in the methods section does not match the explanation in the results section, ...