Although more and more women are surviving breast cancer, the disease is becoming more common, particularly at younger ages. Anew reportshows the breast cancer rate rose by 1% annually from 2012 to 2021, with even greater increases among women under age 50 and a startling jump even among women...
Several studies have shown that breast cancer arising at young age is associated with worse prognosis. Mounting evidence suggests that they are enriched with more aggressive breast cancer subtypes, notably triple-negative or basal-like tumors. However, this does not appear to explain fully the worse...
We compared oestrogen receptor (ER) and progesterone receptor (PgR) profiles between primary and corresponding contralateral breast cancer (CBC) to investi... D Coradini,S Oriana,L Mariani,... - 《European Journal of Cancer》 被引量: 136发表: 1998年 Immunoelectrophoretic and immunohistochemical ch...
A Biological Child Does Not Repair the Injustice of Breast Cancer at a Young AgeGrazia De MicheleI was diagnosed with invasive breast cancer in November 2010, at the age of 30. The diagnosis came totally unexpected. I was really young and there was not a single case of breast cancer in ...
A history of difficulty becoming pregnant and younger age were associated with higher odds of fertility concerns in multivariable modeling. “Many young women with newly diagnosed breast cancer are concerned about fertility in a way that impacts their treatment decisions. Concerns were discussed, b...
Studies from Africa indicate that African women have a high proportion of high grade tumors with an aggressive subtype, e.g., triple-negative breast cancer (TNBC) [4, 5]. These tumors develop at a young age with an advanced stage distribution [5]. Many studies from the U.S. have demons...
Young age at onset is an independent negative prognostic factor in breast cancer. Further studies are required to develop new therapeutic strategies for YA breast cancer patients. From MEDLINE®/PubMed®, a database of the U.S. National Li...
Young age breast cancer (YABC) has unique clinical and biological features that are not seen in older patients. Breast tumor biology is more aggressive and is associated with an unfavorable prognosis in younger women. The diagnosis of breast cancer is often delayed, resulting in their initial pres...
Young Age as a Prognostic Factor for Operable Breast Cancer: Significance of Molecular Subtype in Recurrence-Free Survival Background: Breast cancer is uncommon in young women. Biology of the disease in this age group is poorly understood and the prognostic significance of young age at diagnosis re...
We recruited women (aged 47–73 years) into the PROCAS (Predicting Risk Of Cancer At Screening; Manchester, UK: 2009–2013) Study. In 47,042 women, we determined BMI at baseline and (by recall) at age 20 years, and derived weight changes. We estimated hazard ratios (HRs) and 95% co...