Cancer stagingis the process of determining how muchcanceris within the body (tumor size) and if it has spread. Forbreast cancer, this might take the form of clinical (pre-surgical) staging or pathologic (surgical) staging. Breast cancer is classified by stages. There are five stages of bre...
Breast tumor progression, Tumor size, Three-dimensional in vitro models, Epithelial-mesenchymal transition, E-cadherinTumor size is strongly correlated with breast cancer metastasis and patient survival. Increased tumor size contributes to hypoxic and metabolic gradients in the solid tumor and to an ...
breast cancerAtom RSS Feed Breast cancer articles within Cell Death & Disease FeaturedArticle 18 December 2024 | Open Access Epoxy metabolites of linoleic acid promote the development of breast cancer via orchestrating PLEC/NFκB1/CXCL9-mediated tumor growth and metastasis Kai-Di Ni , Xian Fu...
thus allowing invasion from one 3D matrix to another, and (2) establish distinct regions of tumor and stroma cell/ECM compositions, with a clearly demarcated tumor invasion front, thus allowing us to quantitatively analyze progression of cancer cells into the stroma at a tissue or single-cell le...
Induction chemotherapy (IC) provides in more than 20% of cases a complete shrinkage of the tumor. This down staging is a new challenge for the surgeons for breast conservative procedure. Although, IC has become the standard of care for breast cancer T2 > 3 cm T3 N0 N1 M0. No guidelines...
Breast cancer is the most common cancer in women globally, and tumor size measured as the largest diameter of the tumor focus is currently used in tumor–lymph node–metastasis (TNM) staging for prognosis and treatment decisions. The present study utilized the tumor-to-breast volume ratio (TBR...
www.nature.com/scientificreports OPEN Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment received: 13 June 2016 accepted: 07 September 2016 Published: 28 September 2016 Danh Truong1, Julieann Puleo2, Alison Llave1, Ghassan Mouneimne2, Roger D. Kamm3,...
切缘阳性与患侧乳房肿瘤复发(ipsilateral breast tumor recurrence, IBTR)增加至少2倍相关 切缘阴性患侧乳房肿瘤复发即达最低;再增加切缘宽度不显著降低复发风险 使用全身治疗降低IBTR率;对于未接受辅助性全身治疗的患者,增宽阴性切缘没必要 生物亚型不提示需要增宽阴性切缘 ...
et al. Tumor-infiltrating endothelial cells and endothelial precursor cells in inflammatory breast cancer. Int. J. Cancer 99, 344-351 Inflammatory breast cancer (IBC) is a specific type of breast tumor that generally has a poor prognosis, in spite of recent advances in treatment. In the ...
Introduction Studies in xenograft models and experimental models of metastasis have implicated several β3 integrin-expressing cell populations, including endothelium, platelets and osteoclasts, in breast tumor progression. Since orthotopic human xenograft models of breast cancer are poorly metastatic to bone...