Males at-risk for the BRCA1-gene, the psychological impact. Psycho-oncology 1996; 5: 251 ± 257.DudokdeWit AC, Tibben A, Frets PG, Meijers-Heijboer EJ, Niermeijer MF (1996): Males at-risk for the BRCA1-gene, the psychological impact. Psycho-Oncology 5:251-257....
"These data will help to optimize medical care in male BRCA1 and BRCA2 PV carriers," Dr. Ottini said. "In particular, screening and surveillance programs in men with BRCA1 and BRCA2 PVs should be tailored in light of these gene-specific cancer phenotype differences." "Overall," she conclu...
"Not enough men are getting genetic testing to see if they carry a BRCA1 or BRCA2 gene variant that increases their cancer risk," said lead author Heather Cheng, MD, Ph.D., the director of the Fred Hutch Prostate Cancer Genetics Clinic. "And the men who know they are carriers get tes...
Impact of germline DNA repair gene variants on prognosis and treatment of men with advanced prostate cancer Article Open access 06 November 2023 Germline sequencing in men with metastatic castration-resistant prostate cancer from the BARCODE2 study reveals a wide range of pathogenic variants in DNA...
18、-jarai z,leongamornlert d,saunders e,et al.brca2 is a moderate penetrance gene contributing to young-onset prostate cancer:implications for genetic testing in prostate cancer patientsj.british journal of cancer,2011,105(8):1230-1234.6 agalliu i,gern r,leanza s,et al.associations of hi...
Google Share on Facebook BRCA1 Also found in:Thesaurus,Medical,Acronyms,Encyclopedia,Wikipedia. Related to BRCA1:BRCA2 n. A gene that is associated with the development of familial breast cancer when inherited in a defective state. [br(east) ca(ncer) 1.] ...
Hum Mol Genet 2003; 12: R271-7.Hohenstein P, Fodde R (2003) Of mice and (wo)men: genotype- phenotype correlations in BRCA1. Hum Mol Genet 12(Spec No 2... P Hohenstein - 《Human Molecular Genetics》 被引量: 0发表: 2003年 Germline mutations of the BRCA1 gene in breast and ...
Women carriers of mutations in the tumor suppressor gene, BRCA1, have an up to 80% risk of developing breast cancer, as well as a 40% risk of ovarian cancer. Men who develop breast cancer are frequently BRCA1 mutation carriers. Moreover,... I Fernandezgarcia,P Ameri,MH Barcelloshoff,....
variation by the location of PVs within theBRCA2gene. By contrast, there was no significant variation in the reported overallBRCA1RR estimates by the ethnic ancestry of the study participants. The studies in Ashkenazi Jewish men reported exclusively on the two Ashkenazi founder PVs c.68_69delAG...
As a result of cancer genome testing, two genes (BRCA1, BRCA2) belonging to the homologues recombination gene family with germline pathogenic variants (gPVs) were detected in a total of 30 Japanese male patients (96.68%: 30/31) with advanced/metastatic breast cancer. In one Japanese male ...