If a mutation is found in the cancer patient, other family members can be tested for that particular gene mutation. The patient’s parents, children, brothers, and sisters all have a 50% chance of having the same mutation. Finding a BRCA Gene Mutation Test How to get tested If you are ...
检索时限起始于1990年1月,截至2023年8月,英文文献检索词主要包括BRCA1/2、hereditary breast cancer、hereditary ovarian cancer、germline mutation、screening test、population screening、BRCAscreening、cancer risk assessment、cancer susceptib...
Initial results from participants who completed both the pretest baseline and the 1-2 week posttest follow-up interviews are reported. Gene mutation carriers manifested significantly higher levels of test-related psychological distress, as measured by the Impact of Event Scale, when compared with non...
检索时限起始于1990年1月,截至2023年8月,英文文献检索词主要包括BRCA1/2、hereditary breast cancer、hereditary ovarian cancer、germline mutation、screening test、population screening、BRCA screening、cancer risk assessment、cancer susceptibility、genome sequencing、variant classification、genetic counseling、quality...
检索的英文数据库为PubMed和Embase,中文数据库包括中国生物医学文献数据库、中国知网和万方数据库,检索时限起始于1990年1月,截至2023年8月,英文文献检索词主要包括BRCA1/2、hereditary breast cancer、hereditary ovarian cancer、germline mutation、screening test、population screening、BRCAscreening、cancer risk assessment...
检索的英文数据库为PubMed和Embase,中文数据库包括中国生物医学文献数据库、中国知网和万方数据库,检索时限起始于1990年1月,截至2023年8月,英文文献检索词主要包括BRCA1/2、hereditary breast cancer、hereditary ovarian cancer、germline mutation、screening test、population screening、BRCA screening、cancer risk assessmen...
Who (and what) to test forBRCAmutation The value of gBRCA1/2m testing for cancer risk reduction in breast and ovarian cancer is well-established.17,18,19To date, researchers from the Breast Cancer Information Core (https://research.nhgri.nih.gov/bic/) have collated more than 1800 mutation...
Wooster R, Neuhausen SL, Mangion J, et al. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science. 1994;265(5181):2088-2090. DOI: 10.1126/science.8091231 Venkitaraman AR. Functions of BRCA1 and BRCA2 in...
The identification process includes allele specific sequence-based assays of known sequence variations. The methods can be used for efficient, and accurate detection of a mutation in a test BRCA1 gene sample for diagnostic and therapeutic purposes....
et al. Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families. Cancer Res. 60, 390–394 (2000). CAS PubMed Google Scholar Baria, K. et al. Correspondence re: A. Rothfuss et al. Induced micronucleus ...