does.About half of the patients with brain tumors appear to be over 60 years of age.In this review article, Glioblastoma multiform, as the most common malignant tumor of the central nervous system in elderly is discussed in details of definition, prognosis, diagnosis, treatment and differential ...
Central nervous system;Elderly;Glioma;Leptomeningeal;Lymphoma;Meningioma;Older Definition Primary brain tumors are thought to originate from neuroglial progenitor cells of the central nervous system (CNS). The current World Health Organization (WHO) classification for brain tumors was published in 2016 (...
Tumor-specific antigens refer to antigens that are expressed only by tumor cells, but not by normal tissues. EGFRvIII, introduced in the targeted therapy section, is a tumor-specific antigen. The vaccine peptide rindopepimut was synthesized according to the small amino acid sequence around the ...
elderly [10]. Worldwide, about 3 per 100,000 persons suffer from some form of brain tumor yearly, with males dominating the list [11]. Brain cancer is estimated to feature among the top ten leading causes of cancer-related deaths globally in 2023 [12]. According to the statistics of the...
among the elderly over 50 years old, Glioblastoma (GBM) has high heterogeneity and resistance to radiotherapy and chemotherapy, and the median survival period after treatment is only 15 months. An important reason for the poor prognosis of GBM is the lack of effective early diagnosis and ...
Abstract Dynamic susceptibility contrast (DSC) MRI plays a pivotal role in the accurate diagnosis and prognosis of several neurovascular diseases, but is limited by its reliance on gadolinium, an intravascularly injected chelated metal. Here, we determined the feasibility of measuring perfusion using a...
Karapanayiotides T, Piechowski-Jozwiak B, Van Melle G, Bogousslavsky J, Devuyst G. Stroke patterns, etiology, and prognosis in patients with diabetes mellitus. Neurology. 2004;62:1558–62. ArticlePubMedGoogle Scholar Zhang L, Li X, Wolfe CDA, O’Connell MDL, Wang Y. Diabetes as an in...
Their classification has undergone major restructuring in the 2016 version of the WHO classification of CNS tumours,2 with a subsequent effect on diagnostic criteria, diagnostic testing approaches, grading, prognosis, and treatment planning. The incorporation of both molecular and histological parameters ...
Intracranial metastases are the most frequent brain tumor with recurrence rates after treatment of around 40–60%. Age is still considered a determinant of treatment and prognosis in this pathology. Recent studies analyzing the impact of metastasectomy i
However, the worldwide increase in life expectancy led to a significant increase in the elderly population and age-related diseases. For instance, the senior population in Singapore and Malaysia is anticipated to rise by 372% and 277%, respectively, by the year 2030. In comparison, by the ...