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Several observations support the hypothesis that differences in synaptic and regional cerebral plasticity between the sexes account for the high ratio of males to females in autism. First, males are more susceptible than females to perturbations in genes
The maintenance of adequate blood flow to the brain is critical for normal brain function; cerebral blood flow, its regulation and the effect of alteration in this flow with disease have been studied extensively and are very well understood. This flow is
Brain inflammation plays a key role in neurological disease. Although much research has been conducted investigating inflammatory events in animal models, potential differences in human brain versus rodent models makes it imperative that we also study th
MDD pathogenic effects on large-scale brain networks and alterations in functional connectivity [5,6,7,8,9,10,11,12] is an advancing area of study. Typical treatments include pharmacotherapy, psychotherapy, and therapeutic brain stimulation [13]. Conventional antidepressants (i.e., SSRIs, SNRIs...
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