National Brain Injury Awareness Month focuses on the millions affected by brain injuries, whether from accidents, falls, sports, or other causes. It goes
Traumatic brain injury (TBI) affects millions of people worldwide, many of whom are affected with post-TBI mood disorders or behavioral changes, including aggression or social withdrawal. Diminished functionality can persist for decades after TBI and delay rehabilitation and resumption of employment. It...
Dragon's blood may have radioprotective effects in radiation-induced rat brain injury. Radiat Res, 2012; 178, 75-85. doi: 10.1667/RR2739.1 [81] Floden AM, Li S, Combs CK. Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA...
Traumatic brain injury (TBI) is a common phenomenon, accounting for significant cost and adverse health effects. While there is information about focal pathologies following TBI, knowledge of more diffuse processes is lacking, particularly regarding how
week after cerebral ischemia [276]. In the MCAO model, the phenotypic transformation of CCR2 + monocytes to a more activated state after infiltration into ischemic tissues was found at 14 days postinjury, suggesting that monocytes/macrophages play a pleiotropic role in mediating the injury ...
S1, after 4 weeks of CUMS induction, the sucrose preference rate of mice was significantly reduced in the 4th week (padj = 9.52e−04), indicating that the CUMS modeling was successful. Meanwhile, 30 mg/kg (padj = 8.94e−04) and 60 mg/kg (padj = 0.03) instead of 15 mg/kg ...
administered testosterone causes male brain development to occur. In the absence of either, the rat ends up with a female brain, and female adult behavior despite being physically and genetically male. The period of development is roughly equivalent to gestational week 20 through birth during human...
which are far smaller than the others and are characterized by their spidery shape and multiple branches. It is only when the brain is damaged in adulthood, he suggested, that microglia spring to life—rushing to the injury, where it was thought they helped clean up the area by eating dama...
which include traumatic brain injury (TBI)3, stroke4, surgical resection for cancer5, and epilepsy6, can result in significant damage to the cerebral cortex, leading to a range of symptoms, including cognitive dysfunction7,8,9,10, motor impairment11,12,13,14and difficulty communicating15,16,17...
We test this hypothesis by examining the influence of brain injury (strokes) on the criticality of neural dynamics estimated at the level of single participants using directly measured individual structural connectomes and whole-brain models. Lesions engender a sub-critical state that recovers over ...