It has been speculated that brain activities might directly control adaptive immune responses in lymphoid organs, although there is little evidence for this. Here we show that splenic denervation in mice specifically compromises the formation of plasma c
Brain control of humoral immune responses amenable to behavioural modulation. Nature 581, 204–208 (2020). Article CAS PubMed Google Scholar Nevin, J. T., Moussa, M., Corwin, W. L., Mandoiu, I. I. & Srivastava, P. K. Sympathetic nervous tone limits the development of myeloid-...
(1979) Humoral immune response to melanoma- associated membrane antigen and fetal brain antigen demonstrated by indirect mem- brane immunoflourescence. I. Cancer Immunol. Immunother., 6, 33-39.Irie et al., Humoral immune response to melanoma associated membrane antigen and fetal brain antigen ...
Journals & Books Help Search My accountSign inBrain Blood Vessel In subject area: Immunology and Microbiology Featured on this page Chapters and Articles You might find these chapters and articles relevant to this topic. Basic Sleep Concepts, Science, Deprivation, and Mechanisms...
[47]. Germ-free mice display learning and memory deficits as well as impaired BBB function. Gut microbiota can impact the gut–brain axis via neural, humoral, and immune-mediated routes[48]. Signaling via vagal afferents has been demonstrated in studies where behavior changes associated with ...
of the spectrum, acute manifestations of autonomic dysfunction, triggered by vascular, inflammatory, or traumatic damage to the ans or as adverse effects of medications, present as signs of autonomic hyperactivity. this includes an excessive control over cardiovascular functions, which can also become ...
Communication between the brain and gut is complex and involves multiple systems including the brain cortex, hypothalamus, pituitary and adrenal glands. These structures are closely linked either by the peripheral nervous system or through neurohumoral stimuli and distinct responses have been shown in he...
The immune system develops rapidly immediately after birth. For example, mice are not able to produce detectable levels of humoral antibodies in response to antigen until after one week of age, and the antigen-presenting dendritic cells do not reach normal levels as it is in adult rodent until...
Canpolat E, Lynes MA: In vivo manipulation of endogenous metallothionein with a monoclonal antibody enhances a T-dependent humoral immune response. Toxicol Sci. 2001, 62: 61-70. Article CAS PubMed Google Scholar Lynes MA, Borghesi LA, Youn JH, Olson EA: Immunomodulatory activities of extracell...
of age (less than 10%) [24]. They play a key role in the control of viral infection [36], as exemplified during lymphocytic chroriomeningitis virus (LCMV) infection, where meningeal macrophages become infected and restrain viral infection to the meninges through an interferon response [36]. ...