AimTo determine rates of cerebral atrophy in individuals with symptoms of memory loss but no objective cognitive impairment (SNCI) and their association with future cognitive decline.MethodsThirty-two SNCI subjects, 16 with mild cognitive impairment (MCI) and 27 control subjects had clinical assessmen...
The role of cognitive and brain reserve in memory decline and atrophy rate in mid and late-life: The SMART-MR study - ScienceDirectJet M.J. Vonk PhD a bRashid Ghaznawi MD a cMaarten H.T. Zwartbol MD a cYaakov Stern PhD bMirjam I. Geerlings PhD a...
SIENA has been extended to a single time-point method (Structural Image Evaluation, Using Normalization, of Atrophy Cross-sectional, SIENAX)18, which provides global normalized brain volume (NBV), gray matter volume (GMV) and white matter volume (WMV). FreeSurfer, which measures cortical ...
In brain tissue, atrophy describes a loss of neurons and the connections between them. Atrophy can be generalized, which means that all of the brain has shrunk; or it can be focal, affecting only a limited area of the brain and resulting in a decrease of the functions that area of the ...
New research has found concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline in people who are at genetic risk for the condition. Moderate-to-severe traumatic brain injury is one of the strongest environmental risk factors for developing neurodegenerative diseases such as...
Discussion: Atrophy subtypes categorization predicted different subsequent patterns of cognitive decline and rates of conversion to distinct etiologies of dementia in persons attending memory clinics.doi:10.1002/alz.12231Vincent PlancheVincent Bouteloup
Central obesity is selectively associated with cerebral gray matter atrophy in 15,634 subjects in the UK Biobank ArticleOpen access10 February 2022 Metabolism-related brain morphology accelerates aging and predicts neurodegenerative diseases and stroke: a UK Biobank study ...
Plasma pTau181 and WM volume showed a negative association in the corpus callosum and the frontal and temporal lobes (Fig. 3c). When correcting for random slopes, the results were identical. Fig. 3 Association between plasma pTau181 and rate of brain atrophy in AD-related areas. a There...
P. Old brains come uncoupled in sleep: slow wave-spindle synchrony, brain atrophy, and forgetting. Neuron 97, 221.e4–230.e4 (2018). Google Scholar Fell, J. & Axmacher, N. The role of phase synchronization in memory processes. Nat. Rev. Neurosci. 12, 105–118 (2011). CAS PubMed...
et al. Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study. Ann. Neurol. 57, 789–794 (2005). This large population-based study showed that diminished cerebral blood flow precedes cognitive decline and hippocampal atrophy. Article PubMed Google Scholar Chen, Y. et al. ...