In advanced cases, CTE can lead to severe cognitive decline, resembling dementia. How is CTE diagnosed? Currently, CTE can only be definitively diagnosed after death through an autopsy, in which pathologists id
Sex is the final universal biological variable of AD, as females develop AD at almost twice the rate of males and, importantly, female sex exacerbates the effects of APOE4 on AD risk and rate of cognitive decline. Therefore, this review evaluates the importance of context for understanding the...
Brain scans:Positron emission tomography helps see the activity of the thalamus region of the brain that is affected by fatal insomnia.MRIhelps find out atrophy (damage) in the brain. How to treat fatal familial insomnia There is no cure for fatal familial insomnia. ...
In DECIDE (NCT01064401), 1841 patients with active RRMS were randomized (1:1) to either 150 mg DAC-HYP or intramuscular IFNβ-1a for 96–144 weeks [32]. DAC-HYP significantly reduced the ARR (= pSE), the number of new GELs and T2 lesions, the brain atrophy, and the risk of inc...
If the diagnosis of peripheral vertigo is uncertain, it may be necessary to consult a vestibular physical therapist to help make the diagnosis and also treat the patient at the same time. Some cases of vertigo may require anMRIorCT scanof the brain and inner ears to exclude a structural prob...
Researchers have long been attempting to identify and validate specific biomarkers for Alzheimer’s disease (AD). AD is a neurodegenerative disorder that is characterized by brain atrophy resulting from neuronal loss. It is typically diagnosed following a series of clinical assessments that include ...
A study in adults with high homocysteine levels and mild cognitive impairment found that reducing homocysteine levels slowed brain atrophy in regions associated with cognitive decline. Treating anemia Anemia is a condition in which the blood has too few red blood cells. It can cause fatigue, short...
is not a specific disease, but rather a word used to refer to a variety of symptoms involving memory loss, cognitive impairment, and functional difficulties, often in older adults. Dementia symptoms can be directly caused by damage to or loss of nerve cells and their connections in the b...
decline in cognitive domains seen in non-diseased elderly. Characteristic alterations in the ultrastructure of myelin coupled with evidence of inflammatory processes present in the white matter of several different species suggest that specific molecular events within brain white matter may better explain ...
Alzheimer’s disease (AD) is regarded as a neurodegenerative disease, and it has been proposed that AD may be a systemic disease. Studies have reported associations between non-neurological diseases and AD. The correlations between AD pathology and systemic (non-neurological) pathological changes are...