Neurons in the rat brain and spinal cord labeled after pseudorabies virus injected into the external urethral sphincter. J Comp Neurol. 1996; 375 :502–517.Nadelhaft, I., and Vera, P.L. (1996). Neurons in the rat brain and spinal cord labeled after pseudorabies virus injected into the ...
stroke, and seizures. CCMs are thought to be initiated by endothelial cell (EC) loss of any one of the threeCcmgenes:CCM1 (KRIT1), CCM2 (OSM), or CCM3 (PDCD10). Here we report that mice with a brain EC-specific deletion ofPdcd10(Pdcd10BECKO...
Recent work revealed that estrogen receptor 1 (ESR1)-expressing neurons in the preoptic area (POA) and the ventromedial hypothalamus (VMH) participate in mouse USV [44,45,46,47]. In addition, motor neuron pools in the brain stem and spinal cord that control laryngeal and respiratory muscles ...
In addition, tissues of the brain, abdomen, spine, and intestine were fixed in 4% (w/v) PFA overnight and sliced in 50 μm sections using a CM1950 Leica cryostat (Leica Biosystems, Germany). Fluorescence signals of Cy3-MSNs and FITC-labeled Bifidobacterium in tissues were observed by ...
Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding Science, 360 (2018), pp. 176-182 Google Scholar Rudy et al., 2011 B. Rudy, G. Fishell, S. Lee, J. Hjerling-Leffler Three groups of interneurons account for nearly 100% of neocortical GABAergi...
Neurons are generally associated with the brain, but amazingly, yourintestines contain 100 million of them— more than either your spinal cord or peripheral nervous system! "More than 90% of our total serotonin and 50% of our dopamine is found in our intestines. ...
We compared organoid transcriptional profiles to datasets of 21 different human fetal organs during the first and second trimester (Roost et al., 2015). Pearson’s correlation analysis showed that organoids from all four time points strongly correlated with fetal brains and spinal cord, with less ...
In order to avoid bias caused by different topological analysis methods, four methods were used for analysis: MCC, DMNC, MNC, and EPC. The results were then merged and analyzed using the “VennDiagram” package, resulting in the identification of the hub genes (Fig. 4). The upregulated ...
Despite the fundamental importance of understanding the brain’s wiring diagram, our knowledge of how neuronal connectivity is rewired by traumatic brain injury remains remarkably incomplete. Here we use cellular resolution whole-brain imaging to generat
To train and validate our model, we randomly sampled and VR-annotated 48 × 100³ voxel patches (referring to 5,889 cells) from a c-Fos-labeled brain. From these we trained a 3D BasicUNet (Extended Data Fig. 2d). In addition, we trained recent larger segmentation models, such as...