1950年代在美国开始有人希望利用这种特性发展癌症治疗方式;理论上,只要能合成出会被癌细胞大量摄取的硼化合物,再以中子射线引发癌细胞中硼-10的核分裂,如此便可以极精准地杀死癌细胞,并几乎不波及周边的组织。这种以硼-10核分裂为基础的中子捕获治疗称为“硼中子捕获治疗(Boron Neutron Capture Therapy, BNCT)”。
Boron Neutron Capture Therapy (BNCT) is a unique form of radiotherapy that carries a potential for a significant improvement in therapeutic gain. That technique involves the concurrent presence of thermal neutrons (energy ? 1 eV) and a 10B capture agent. Their interaction generates heavy particles ...
硼中子俘获疗法（Boron Neutron Capture Therapy，简称BNCT）是一种基于中子照射的放射治疗技术，主要用于治疗某些恶性肿瘤。这种治疗方法的基本原理是将一种含有硼-10的化合物注入到患者体内，该化合物会聚集在肿瘤组织内。然后，患者接受中子照射，中子与硼-10发生反应，释放出α粒子和锂核，这些粒子的能量足以摧毁肿瘤...
硼中子俘获治疗(boronneutron capture therapyBNCT)是一种基于含10B硼药和中子照射的二元靶向肿瘤治疗方法.BNCT治疗肿瘤首先对患者注射硼药,使之聚集于肿瘤部位,然后利用热中子或超热中子束对肿瘤部位进行照射,10B与中子碰撞发生核裂变反应产生具有高传能线密度的a粒子和反冲7锂从而选择性地杀死肿瘤细胞.日本已于2020年...
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BNCT,即硼中子俘..BNCT,即硼中子俘获治疗(Boron Neutron Capture Therapy,简称:中子线治疗)。硼中子俘获治疗通过在肿瘤细胞内的原子核反应来摧毁癌细胞。它的原理是这样的:先给病人注射一种含
Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when boron-10, is irradiated with low energy-thermal neutrons to yield high linear energy transfer alpha particles and recoiling lithium-7 nuclei. Clinical interest in BNCT has focused primarily on the treatment of...
“硼药治疗”的专业术语其实是“硼中子俘获治疗(boron neutron capture therapy,BNCT)”,属于放疗的一种。其原理可以表示为10B(硼)+ n(中子)→ 7Li(锂)+4He(α粒子),大概可以理解为,在中子的照射下,肿瘤内的10B发生核裂变,产生α粒子和7Li,从而杀灭肿瘤。
Tumor cell destruction in boron neutron capture therapy (BNCT) is due to the nuclear reaction between 10 B and thermal neutrons. The thermal neutrons have ... H Nakamura - 《Methods in Enzymology》 被引量: 33发表: 2009年 Tissue Disposition of 5o 〤arboranyluracil—A Novel Agent for the ...
Boron neutron capture therapy (BNCT) has a unique property of tumor-cell-selective heavy-particle irradiation. BNCT can form large dose gradients between cancer cells and normal cells, even if the two types of cells are mingled at the tumor margin. This property makes it possible for BNCT to...