1950年代在美国开始有人希望利用这种特性发展癌症治疗方式;理论上,只要能合成出会被癌细胞大量摄取的硼化合物,再以中子射线引发癌细胞中硼-10的核分裂,如此便可以极精准地杀死癌细胞,并几乎不波及周边的组织。这种以硼-10核分裂为基础的中子捕获治疗称为“硼中子捕获治疗(Boron Neutron Capture Therapy, BNCT)”。
The use of cells as carriers for the delivery of nanoparticles is a promising approach in anticancer therapy, mainly due to their natural properties, such as biocompatibility and non-immunogenicity. Cellular carriers prevent the rapid degradation of nano
Boron neutron capture therapy (BNCT) in an oral precancer model: therapeutic benefits and potential toxicity of a double application of BNCT with a six-week interval Oral Oncol, 47 (2011), pp. 1017-1022 View PDFView articleView in ScopusGoogle Scholar 23 L.W. Wang, S.J. Wang, P.Y. ...
BNCT是英语Boron neutron capture therapy首字母缩写,翻译过来就是硼中子俘获疗法。 很多媒体报道,BNCT被誉为继化疗、放疗、靶向疗法、免疫疗法之后癌症的的“第五疗法”,可以精准打击癌细胞,治疗效果效果超过靶向和免疫疗法,而且副作用小,一切看上去似乎都无可挑剔,难不成癌症治疗难题被攻克了? 本质上说,硼中子俘获疗...
154 MORPHOLOGICAL ASSESSMENT OF BORON NEUTRON CAPTURE THERAPY (BNCT) EFFECTIVENESS ON EXPERIMENTAL BRAIN TUMORSProteinsSequence AlignmentEvolution, MolecularConserved SequenceProtein ConformationSequence Homology, Amino AcidAmino Acid SequenceComputer SimulationMolecular Sequence Data...
A critical assessment of boron neutron capture therapy: an overview J Neurooncol, 62 (2003), 10.1007/bf02699929 Google Scholar [7] RV Dorn III Boron neutron capture therapy (BNCT): a radiation oncology perspective Int J Radiat Oncol Biol Phys, 28 (1994), pp. 1189-1201 View PDFView articl...
The present invention relates to new anti-cancer compounds and in particular to new compounds for use in nuclide activation therapy, such as neutron capture therapy. Specifically this invention provides a conjugate having the general formula P-(L-NAT) n wherein P represents an N-hydroxypropylmethac...
RaySearch offers support to plan for Boron Neutron Capture Therapy (BNCT)*. BNCT is a unique type of radiation therapy that enables targeting of cancer at the cellular level. BNCT planning in RayStation is developed together with Sumitomo, Neutron Therapeutics and TAE Life Sciences. *Subject to ...
The results demonstrate that the effect of fast neutrons on cell survival in cell culture can be enhanced by boron neutron capture reaction. Even with lower enhancement ratios, the concept of NCT assisted fast neutron therapy may successfully be applied for tumor treatment with the Essen cyclotron....
硼中子俘获疗法（Boron Neutron Capture Therapy，简称BNCT）是一种基于中子照射的放射治疗技术，主要用于治疗某些恶性肿瘤。这种治疗方法的基本原理是将一种含有硼-10的化合物注入到患者体内，该化合物会聚集在肿瘤组织内。然后，患者接受中子照射，中子与硼-10发生反应，释放出α粒子和锂核，这些粒子的能量足以摧毁肿瘤...