In silico biology of bone modelling and remodelling: adaptation. Philos Trans A Math Phys Eng Sci 2009;367(1895):2011e30.Gerhard, F. A., Webster, D. J., van Lenthe, G. H., and Muller, R. (2009). In silico biology of bone modelling and remodelling: adaptation. Philos. Trans. A...
and which constantly undergoes modelling and remodeling through the coordination of osteoclasts, osteoblasts, and osteocytes. Osteoclasts, derived from mononuclear hematopoietic myeloid lineage cells, are responsible for bone resorption.1Osteoblasts, accounting for the (4–6)% of total resident cells in t...
In silico biology of bone modelling and remodelling: adaptation. Philos. Trans. A Math. Phys. Eng. Sci. 367, 2011–2030 (2009). Article Google Scholar Riggs, M. M. & Cremers, S. Pharmacometrics and systems pharmacology for metabolic bone diseases. Br. J. Clin. Pharmacol. 85, 1136–...
During growth, bone modelling and remodelling optimize strength, by depositing bone where it is needed, and minimize mass, by removing it from where it is not. The population variance in bone traits is established before puberty and the position of an individual's bone size and mass tracks ...
A histomorphometric study of alveolar bone modelling and remodelling in mice fed a boron-deficient diet. Boron An Overlooked Micronutrient Williams et al., (2000 and 2004) postulated that rapid bone modelling and remodeling in modern birds with inadequate supply of mineral (primarily Ca and phosphor...
Remodelling is bone turnover, also performed by osteoclasts and osteoblasts. The processes of modelling and remodelling are induced by mechanical loads, predominantly muscle loads. Osteoblasts develop from mesenchymal stem cells. Many stimulating factors are known to activate the differentiation. Mature ...
Although the quality and quantity of tissue strains and the mechanisms responsible for bone modelling and remodelling are still a topic of controversy and argument,11., 12. there is a consensus that mechanical factors and loading history do play a substantial role as a feedback mechanism in bone...
The bone modelling and remodelling required for the disappearance of a visible lower limb deformity takes many months or years compared to resolution of the metabolic perturbations and radiographic signs that define active rickets. In summary, this survey of children < 18.0 years in West Kiang, The...
Use of two biochemical markers of bone metabolism, bone alkaline phosphatase (b-ALP) and cross linked C-telopeptide of type I collagen (ICTP), in the asses... Several authors considered biochemical markers of bone turnover as a non-invasive monitoring of bone modelling-remodelling activity. Radi...
Bone as most of living tissues is able, during its entire lifetime, to adapt its internal microstructure and subsequently its associated mechanical properties to its specific mechanical and physiological environment in a process commonly known as bone remodelling. Bone is therefore continuously renewed ...