19. Demonstration of osteoclasts at different stages of the bone remodelling cycle: A histological and in situ biochemical study of adult human bonedoi:10.1016/8756-3282(91)90115-YR.A. Dodds and I.E. James and S. Walsh and M. Gowen...
The bone remodelling cycle.The bone remodelling cycle lasts 150–200 days and is primarily mediated by osteoblastic signals which promote the differentiation and maturation of osteoclast precursors. Activated osteoclasts create resorption pits with low pH to dissolve the inorganic matrix and lysomal enzyme...
a predator–prey model to describe the dynamic interaction between osteoclasts and osteoblasts, using a genetic algorithm–based solution; quantitative reconstruction of the bone remodelling cycle; and the introduction of a feedback mechanism in the bone formation activity to co-regulate bone thickness....
Nonetheless, the pathological mechanisms in all bone-loss involving conditions, while complex, are ultimately mediated through effects on the bone remodelling cycle and therefore, the restoration of tissue and fractures recapitulates many of the ontological events of embryonic skeletal development. Therefore...
6). Taken together, these data demonstrate the ability of the MM HCA to capture the vicious cycle of MM progression in the bone microenvironment over time. Fig. 5: Computational and biological model outputs of cell types in the myeloma bone microenvironment. Computational model outputs of ...
The process of bone remodelling is done by the selective activity of osteoblasts and osteoclasts. They are responsible for the making and destroying...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
Bone cells and the mechanisms of bone remodelling. Bone is a peculiar connective tissue which functionally interacts with many other organs and tissues, including bone marrow, lymphoid tissue, kidney, adipo... FA Del,A Teti,N Rucci - 《Frontiers in Bioscience》 被引量: 65发表: 2012年 The ...
The Law of Bone Remodelling The present work aims at establishing as exhaustively as possible the math ematical, anatomical and clinical bases of the law of bone remodelling and the consequent functional bone shape and remodelling force. Another aim of this work co......
bone remodellingAlthough bones seem inert, however, through the remodelling process, they constantly go through destruction and creation of bone tissue in relation with the mechanical forces that act on them. Bone mechanotransduction intervenes in the perception of the mechanical tensions that occur in...
An over- view of the regulation of bone remodelling at the cellular level. Clin Biochem 2012;45: 863-873.Kular J, Tickner J, Chim SM, Xu J: An overview of the regulation of bone remodelling at the cellular level. Clin Biochem, The Canadian Society of Clinical Chemists, 2012, 45:863-...