PrognosisLiquid biopsyAnimal modelsThe most common site of metastasis in breast cancer is the bone, where the balance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation is disrupted. This imbalance causes osteolytic bone metastasis in breast cancer, which leads to bone ...
The most common site of metastasis in breast cancer is the bone, where the balance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation is disrupted. This imbalance causes osteolytic bone metastasis in breast cancer, which leads to bone pain, pathological fractures, spinal...
In the current study, we aimed to identify risk factors associated with cancer prognosis and to detect the bone metastasis pattern of PCa patients in SEER database and a Chinese hospital. We compared the consistency and difference between SEER data and local hospital data. We were particularly in...
There is no established method for assessing the prognosis of patients with breast cancer and metastasis confined initially to bone. The medical records of 82 patients with breast cancer nad metastasis confined initially to bone were reviewed. The following variables were analyzed at the time when bo...
Bone metastasis is a lethal consequence of breast cancer. Here we used single-cell transcriptomics to investigate the molecular mechanisms underlying bone metastasis colonization—the rate-limiting step in the metastatic cascade. We identified that lymphotoxin-β (LTβ) is highly expressed in tumour ce...
For example, OPN is produced by many breast cancer cells and has a strong clinical correlation with poor prognosis and decreased survival [37]. It can contribute to tumor cell survival, proliferation, adhesion, and migration. In the bone, OPN is involved in the differentiation and activity of ...
Breast cancer is considered to often involve bone metastasis. Early detection and treatment of bone metastasis are essential in improving the prognosis of this disease. In 47 patients with bone metastasis confirmed with bone scintigraphy... S Tanaka,Y Matsumura,M Tanaka,... - 《Kaku Igaku the ...
of Prostate Cancer Site of Bone Metastasis Useful for Prognosis of Prostate CancerSite of Bone Metastasis Useful for Prognosis of Prostate CancerAdministrator
Bone Mechanics in Cancer Chet H.Falk, ...Maureen E.Lynch, inEncyclopedia of Bone Biology, 2020 Introduction Bonemetastasisis a devastating diagnosis with a dismal prognosis. In particular, roughly 3 in 4 patients with advanced breast andprostate cancersdevelop incurable bone metastases (Society, 201...
Skeletal metastases in non-small cell lung cancer: a retrospective study. Lung cancer (Amsterdam Netherlands). 2007;57(2):229–32. Article PubMed Google Scholar Zhang G, Liu Z, Chen Y, Zhang Y. High serum HDGF levels are predictive of bone metastasis and unfavorable prognosis in Non-...