Bone Marrow Specimens From Patients with Immune Thrombocytopenia (ITP) Demonstrate Increased Megakaryocyte-Bound IgG and Increased T-Helper CellsLisa J. ToltlCatherine RossJohn G. KeltonDonald M. Arnold
To investigate the role of co-stimulatory and co-inhibitory molecules on immune tolerance in immune thrombocytopenia (ITP), this study mapped the immune cell heterogeneity in the bone marrow of ITP at the single-cell level using Cytometry by Time of Flight (CyTOF). Thirty-six patients with ITP...
2、s to obtain cells for cytogenetic, flow cytometry or immunocytochemistry studies.5678 The marrow spicules, fat drop, nucleated cells and cells special to the bone marrow;2. The cellularity of bone marrow- the myeloid to erythroid ratio (M:E); 3. The proportions of each cell type and mat...
Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia (ITP) patients treated with romiplostim. Blood. 2009;114(18):3748-3756.Kuter DJ, Mufti GJ, Bain BJ, Hasserjian RP, Davis W, Rutstein M (2009) Evaluation of bone marrow reticulin formation in chronic immune ...
Twenty-four patients sustained platelet counts ≥50×109/L for ≥6months with no ITP medications after discontinuing romiplostim, i.e., they entered clinical remission of their ITP. In conclusion, in patients with ITP receiving romiplostim, bone marrow changes were observed in a small proportion ...
1.Bonemarrowexamination2.Bloodandbonemarrowprofiles ofsomehematologicaldiseases 2 Bonemarrowexamination IndicationsandCounterindications MethodsGeneralprofilesCloseinspectionofbloodcellprecursors 3 Indicationsforbonemarrowexamination 1.furtherworkupofhematologicabnormalitiesobservedinbloodroutinetestorbloodsmear 2.evaluationof...
1) Bone marrow test 骨髓像检查2) Bone marrow examination 骨髓检查 1. Bone marrow examination of 289 patients with fever of unknown origin; 骨髓检查在289例原因不明发热诊断中的价值 2. Clinical application of bone marrow examination in patients with fever of unknown origin; 骨髓检查在诊断不...
Patients with ITP display cytotoxic activity towards platelets, and abnormalities in T cell repertoire. However, there is incomplete understanding of the interactions between T cells and megakaryocytes within the bone marrow. We hypothesized that if T cell or NK cell cytotoxicity against megakaryocytes...
1)Bone marrow aspiration骨髓穿刺 1.Objective:To determine the factors affecting the quality of the bone marrow aspirationg by retrospective analyzing the bone marrow smears.目的:回顾分析两年来的骨髓穿刺检查,了解影响骨髓穿刺取材质量的各种因素。 英文短句/例句 1.BACKGROUND? To explore the advantage of...
ITP ii. Other autoimmune associated (systemic lupus erythematosus, Crohn’s disease, etc.) iii. Viral infections (e.g., SARS-CoV-2) Trilineage bone marrow failure (generalized pancytopenia) 1. Inherited a. FA (associated with chromosomal breakages induced by clastogens, for example, DEB or MM...