Single cellT cellT cell receptorThe immune microenvironment plays an important role in leukemia treatment. However, a specific single-cell profiling of the immune alteration in bone marrow of chronic myeloid leukemia (CML) patients is still lacking. We conduct multi-level single-cell sequencing to ...
Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencingBONE marrow cellsNUCLEOTIDE sequenceBIOLOGICAL researchMACHINE learningLOGISTIC regression analysisBiomedical research often involves conducting experiments on model organisms in the anticipation that the ...
a childhood tumor has been molecularly defined at the primary cancer site, however, the bone marrow (BM) as the metastatic niche of NB is poorly characterized. Here we perform single-cell transcriptomic and epigenomic profiling of BM aspirates from 11 subjects spanning three major NB subtypes and...
文章题目:The bone marrow microenvironment at single-cell resolution发表期刊:nature 发表时间:2019年4月10日 原文链接:https://www.nature.com/articles/s41586-019-1104-8#Bib1 通讯作者是Iannis Aifantis 教授,其研究方主要为Cancer, immunology, stem cell biology, epigenetic regulation, leukemia, tumor micro...
人骨髓单个核细胞BMMC 价格: ￥35/块 产品详情: 人骨髓单个核细胞 BMMC IPHASE Human Bone Marrow Mononuclear Cells Cell Isolation of Bone Marrow Mononuclear Cells... 纯度:100% 包装规格:1ml 用途:Cell Isolation of Spleen Mononuclear Cells,可根据客户需求定制生产不同动物种属的脾脏单个核细胞,骨髓单个核...
We have previously shown that mesenchymal stromal cells (MSC) from individuals harboring a DNMT3A mutation instruct young healthy HSPC and influence their fate in vitro, pointing to a potential role for the bone marrow (BM) microenvironment in progression to myeloid neoplasia. To gain further ...
Here, we generated a single-cell RNA-seq dataset of primary neutrophils from 3-month-old female and male adult mouse bone marrow with biological replicates (n = 2 per sex) (Fig. 1a and Table 1). All the samples in our dataset were handled and processed together to eliminate ...
Bone marrow mesenchymal stromal/stem cells (MSCs) are a heterogeneous population that can self-renew and generate stroma, cartilage, fat, and bone. Although a significant progress has been made toward recognizing about the phenotypic characteristics of M
英文名称 Bone Marrow Mesenchymal Stem Cells 产品编号 PCLR0113-RT 规格 5×105 交货期 10 属性 默认T25瓶,若需1mL冻存管包装请洽询 种属 兔 推荐培养基 CellCM0015-500ml 培养温度 37 运输温度 常温 货期是否稳定 询期 运输和保存 干冰运输及复苏存活细胞 品牌 毕合生物 价格说明 价格:商品...
Recent single cell RNA-seq based evidence further proposes that a subpopulation of Adipoq-labeled marrow adipocytes is critical for supporting marrow vasculature18. Thus, there are context dependent functions of BMAds as a niche component maintaining bone marrow microenvironment. Orphan nuclear receptor ...