Compositions and methods are provided for separating a whole or bone marrow aspirate blood sample from a fraction rich in at least one of the platelets and pluripotent cells. A whole blood sample may be centrifuged in a collection tube comprising a separating substance formulated to settle between...
JERUSALEM, March 7 (Xinhua) -- Israeli researchers discovered that the bone marrow not only produces blood cells and platelets but also responds to inflammation and infection by accelerating the production of immune cells, the Israel Institute of Technology (Technion) said in a statement on Thursday...
Related to Bone marrow aplasia: aplastic anemiaaplastic anemia n. A condition in which the bone marrow fails to generate adequate numbers of new red blood cells, white blood cells, and platelets. It can be caused by a genetic disorder, infection, exposure to radiation or toxic chemicals, or ...
Cryopreservation of Platelets, Bone Marrow and Lymphocytes: Applications for the Transplant RecipientPatients awaiting transplantation have a variety of hematologic disorders. This study examines the abnormalities encoutered and the cryopreserved blood elements that are available for therapy. Anemia......
Bone Marrow In the adult, bone marrow is the major organ for production of erythrocytes, platelets, granular leukocytes, and monocytes. Many lymphocytes also are produced in the marrow and reside in the lymphatic tissues secondarily. In toto, the bone marrow constitutes an organ that rivals the ...
Cancer cells are well-known for their capacity to adapt their metabolism to their increasing energy demands which is necessary for tumor progression. This is no different for Multiple Myeloma (MM), a hematological cancer which develops in the bone marrow (BM), whereby the malignant plasma cells ...
Bone Marrow Necrosis/Inflammation Ischemic and toxic injury to bone marrow results in marrow necrosis and may result in an inflammatory response. Bone marrow necrosis has been associated with a variety of conditions, including septicemia/endotoxemia, drug and toxin exposure, parvovirus and monocytic eh...
a hypoplastic marrow can persist and may become aplastic. The latter event can also result from an infiltration of the marrow, and this scenario should be suspected if the depression in blood count does not occur at a predictable time or if only a limited volume of the bone marrow has been...
Reduced responsiveness of bone marrow megakaryocyte progenitors to plateletヾerived transforming growth factor β1, produced in normal amount, in patients ... ( 1993 ) Reduced responsiveness of bone marrow megakaryocyte progenitors to platelet-derived transforming growth factor β 1, produced in normal ...
Fibrosis of the marrow is always secondary to a primary event which may be clonal or non clonal. Megakaryocytes and platelets form the central arm in myelofibrosis. Haemopoietic stem cells, clonal or activated in various inflammatory processes, immune cells and megakaryocytes (clonal or activated) ...