We hypothesized that low bone density following early adolescent pregnancy persists into young adult life. Methods A cohort of 256 women was identified by chart review. Participants were eligible if they delivered before the age of 16 years and were aged 20 to 45 years at time of study. We ...
Osteoporosis is one of the most common metabolic bone disease among pre- and postmenopausal women. As the precursors of osteoclast cells, circulating monocytes play important role in bone destruction and remodeling. The aim of study is to identify potent
Blood samples were obtained to quantify serum glucose, insulin, total cholesterol, triglycerides, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol. Subjects with BMI Z scores of +3 or −3; values of glucose ≥100 mg/dL, total cholesterol ≥200 mg/dL; HDL...
BC is one of the most common cancers among women. Similarly, in the absence of estrogen or androgen, increased osteoclast activity and bone remodeling lead to the release of osteogenic factors from resorbed bone, creating a favorable environment for the survival and growth of tumor cells. In add...
Scores for the 12-score method concentrated in the range of 6–12, with a mean of 10.33 ± 1.62. The cumulative proportions of new fractures and re-collapse corresponding to each score are shown in Table4, and the line chart based on these data is shown in Fig.3. The score corr...
Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study. BMC Musculoskelet Disord 2010;11:68.Grima DT, Papaioannou A, Airia P, et al. Adverse events, bone mineral ...
e.g. mineral density scores.Vitamin K2andsoy isoflavones, for instance, significantly reduce bone fracture rates without increasing bone density. Scoring high on bone density tests may save a woman from being intimidated into taking dangerous drugs or swallowing massive doses of elemetal calcium, but...
density.14,15,37,51 A quantitative ultrasound has also been used, but probably is still not suitable to monitor the effect of intervention on BMD,58 whereas magnetic resonance imaging also seems to have a potential in future studies in assessing bone geometry.59 For the chronic phase (Table ...
Men and women who were newly diagnosed with low bone density had a higher prevalence than controls of using androgen deprivation therapy and aromatase inhibitors, respectively. Subjects with low bone density were more likely to take DMPA and estrogen or a combination of estrogen and progesterone, ...
al., Inhibition of sclerostin with AMG 785 in postmenopausal women with low bone mineral density: Phase 2 trial results—Abstract presented at the 2012 meeting of the American Society for Bone and Mineral Reasearch (2012). Memorandum C, Munich Diplomatic Conference, Sep. 1 to Oct. 6, 1973....