We hypothesized that low bone density following early adolescent pregnancy persists into young adult life. Methods A cohort of 256 women was identified by chart review. Participants were eligible if they delivered before the age of 16 years and were aged 20 to 45 years at time of study. We ...
Osteoporosis is one of the most common metabolic bone disease among pre- and postmenopausal women. As the precursors of osteoclast cells, circulating monocytes play important role in bone destruction and remodeling. The aim of study is to identify potent
We constructed age- and sex-smoothed reference values for areal bone mineral density (aBMD) of total body less head (TBLH), total body (TB), lumbar spine (LS), and bone mineral apparent density (BMAD) for LS, by means of Generalized Additive Models for Location, Scale and Shape (...
the size of nanomedicines significantly impacts their excretion pathways: particles smaller than 6 nm are usually eliminated via renal filtration, whereas those larger than 500 nm tend to be cleared by the reticuloendothelial system. Hence, the ideal size range for nanocarriers is roughly 20 ~...
The total MAE was 0.025 ± 0.020, which suggests an error magnitude of approximately one-tenth of the intensity range. Figure 6 Mean absolute error (MAE) of image translation for each patient. Full size image Experiments 2 and 3 Figure 7 shows the accuracies of the 2D–3D ...
The population of interest in this study is women of South Asian origin living in Auckland, New Zealand. There is a high incidence of type 2 diabetes in South Asians living in New Zealand; self-reported diabetes is over three times higher for this group compared to national incidence [21]....
Results: NMC occurred in 2 females and 3 males (mean age 14 years, range <1 to 51 y), as masses involving the sciatic nerve (N=4) or brachial plexus (N=1). In 4 of 5 cases, biopsy-confirmed NMC-Fi developed following biopsy or surgical intervention for the NMC. Three (of 5) ...
Taking advantage of the synteny between human genome sequence and the murine introgressed region on chromosome 2, we identified histidine decarboxylase (HDC), the rate-limiting enzyme in the biosynthesis of histamine, as a positional candidate gene for the observed variation in bone density. Notably,...
al., Inhibition of sclerostin with AMG 785 in postmenopausal women with low bone mineral density: Phase 2 trial results—Abstract presented at the 2012 meeting of the American Society for Bone and Mineral Reasearch (2012). Memorandum C, Munich Diplomatic Conference, Sep. 1 to Oct. 6, 1973....
density values over a portion of a vertebra illustrating one method of determining the borders of a vertebra wherein for clarity the density values within a range associated with tissue are shown by the letter "T" and the density values in a range indicating bone are shown by the letter "B...