PM Conforti,MS Kanarek,LA Jackson,... - 《Journal of Chronic Diseases》 被引量: 111发表: 1981年 Migration of asbestos fibres from subcutaneous injection sites in mice. Crocidolite asbestos fibres, suspended in physiological saline, were injected subcutaneously into one or both flanks of 95 CBA...
We then investigated the chromatin accessibility state of the genes that are upregulated. We analysed an ATAC-Seq dataset we had previously generated in WT embryos26and found that the transcription start site (TSS) of genes that are upregulated in themir430−/− + inj MiR430 are high...
112 found a small increase in inflammatory markers in ex vivo LPS-stimulated peripheral blood mononuclear cells from healthy subjects given oral BHB compared with a calorie-free control. On the other hand, a follow-up study by the same group showed no additional effect of BHB on inflammatory ...
Firstly, we found that aRBD-5 lost binding to some of the variants but still contributes to the overall binding when fused to aRBD-2. The precise mechanism will require further determination on the structure of aRBD-2-5 in complex with the variant RBDs. Secondly, we assessed the ...
B Jackson 被引量: 0发表: 0年 A review of studies on androgen and estrogen exposure in fish early life stages: effects on gene and hormonal control of sexual differentiation Estrogenic activities at the two most upstream sampling sites were found to be high enough to negatively impact target ce...
Quantification of MS samples was performed by MaxQuant 1.6.1.0 and Xcalibur Qual Browser. Details can be found in STAR methods. Statistical analysis was performed by Prism GraphPad 7. Details of the statistical analysis performed, exact values of n and what they represent, definitions of the summ...
(1:1000, Molecular Probes™, Invitrogen, Belgium), donkey anti-chicken Cy3 (1:500, Jackson ImmunoResearch) and donkey anti-rabbit Alexa 647 (1:1000, Molecular Probes™, Invitrogen) or donkey anti-mouse Alexa 488 (1:1000, Molecular Probes™, Invitrogen, Belgium) and donkey anti-rabbit ...
containing an amount of bodies generally equivalent to 10%-1000% of the number of leukocytes normally found in an equivalent volume of whole blood. Preferably, the number of bodies administered per delivery to a human patient is in the range from about 500 to about 2.5×109(<250 ng of bodi...
Unexpectedly, by analyzing the T4P-C24 cryoEM structures, we also found that the binding of a nanobody targeting the alpha-beta loop could be altered by amino acid changes in strand β1 of the beta-sheet region. Long side chain amino acids from the beta sheet come in close contact with ...
Fibroblasts differentiate into myofibroblasts, which contain actin similar in structure to the actin found in smooth muscle, and function in wound contraction (96). Myofibroblasts attach to one another and the ECM at the wound edges, and pull on the ECM when they contract, thus reducing the ...